Dr. Blanca Hernández Ledesma

Spanish National Research Council (CSIC), Spain

Email: b.hernandez@csic.es

Qualifications

2002  Pharmacy Ph.D. Degree, Universidad Complutense de Madrid
1998  Pharmacy Degree, Universidad Complutense de Madrid

Publications (Selected)

1. Nobrega de Moura, J.M.L.,Hernández-Ledesma, B., de Almeida, N.M., Hsieh, C.-C., de Lumen, B.O., Johnson, L.A. Lunasin and Bowman-Birk Protease Inhibitor Concentrations of Protein Extracts from Enzyme-assisted Aqueous Extraction of Soybeans.Journal of Agricultural and Food Chemistry(2011) 59, 6940-6946.
2. Hernández-Ledesma, B., Paunero, M., Martínez-Maqueda, D., Recio, I. Evaluation of the antioxidant effect of opioid peptide on intestinal cells. Annals of Nutrition and Metabolism(2011) 58 (suppl. 3) 353.
3. Hernández-Ledesma, B., Ramos, M., Gómez-Ruiz, J.A. Bioactive components of ovine and caprine cheese whey.Small Ruminant Research (2011) 101, 196-204.
4. Hernández-Ledesma, B., Espartosa, D. M., Hsieh, C.-C., de Lumen, B.O. Recio, I. Role of peptide lunasin’s antioxidant activity on its chemopreventive properties.Annals of Nutrition and Metabolism (2011) 58 (suppl. 3) 354.
5. Olivera-Castillo, L., Pérez-Vega, J.A., Gómez-Ruiz, J.A.,Hernández-Ledesma, B.Release of bioactive peptides by simulated gastrointestinal digestion of sea cucumber protein(Isostichopus badionotus). Annals of Nutrition and Metabolism(2011) 58 (suppl. 3) 121.
6. Martínez-Maqueda, D., Miralles, B., Recio, I., Hernández-Ledesma, B. Antihypertensive peptides from food sources: a review. Food & Function (2012) 3, 350-362.
7. Quirós, A.,Hernández-Ledesma, B.,Ramos, M., Martín-Álvarez, P.J., Recio, I. Production of antihypertensive peptide HLPLP by enzymatic hydrolysis: optimization by response surface methodology.Journal of Dairy Science(2012) 95, 4280-4285.
8. Bustos, I., García-Cayuela, T., Hernández-Ledesma, B., Peláez, C., Requena, T., Martínez-Cuesta, C. Effect of flavanol-3-ols on the adhesion of potential probiótica lactobacilli to intestinal cells. Journal of Agricultural and Food Chemistry (2012) 60, 9082-9088.
9. Hernández-Ledesma, B., Hsieh, C-C., de Lumen, B.O. Lunasin, a seed peptide with promising cancer preventive properties.Protein and Peptide Letters (2013) 20, 424-432.
10. Pérez-Vega, J.A., Olivera-Castillo, L., Gómez-Ruiz, J.A.,Hernández-Ledesma, B. Release of multifunctional peptides by gastrointestinal digestion ofsea cucumber(Isostichopus badionotus). Journal of Functional Foods (2013) 5, 869-877.
11. Silveira, S.T., Martínez-Maqueda, D., Recio, I.,Hernández-Ledesma, B. Dipeptidyl peptidase-IV inhibitory peptides generated by tryptic hydrolysis of a whey protein concentrate rich in β-lactoglobulin.Food Chemistry (2013) 141, 1072-1077.
12. Hernández-Ledesma, B., García-Nebot, M. J., Fernández-Tomé, S., Amigo, L., Recio, I. Dairy protein hydrolysates: Peptides for health benefits. International Dairy Journal (2013). In press.
13. Arques, M. C., Marín-Manzano, M. C., Brito da Rocha, L. C.,Hernandez-Ledesma, B., Recio, I., Clemente, A. Quantitative determination of active Bowman-Birk isoinhibitors, IBB1 and IBBD2, in commercial soymilks. Food Chemistry (2014) 155, 24-30.
14. García-Nebot, M. J., Recio, I., Hernandez-Ledesma, B. Antioxidant activity and protective effects of peptide lunasin against oxidative stress in intestinal Caco-2 cells. Food and Chemical Toxicology (2014) 65, 155-161.