Dr. Eran Meshorer
The Hebrew University of Jerusalem, Israel
Email: meshorer@cc.huji.ac.il
Qualifications
2003 Ph.D., Molecular neuroscience, The Hebrew University of Jerusalem
1999 M.Sc., Molecular microbiology, The Hebrew University of Jerusalem
1996 B.Sc., Biology, The Hebrew University of Jerusalem
Publications(Selected)
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Nissim-Rafinia M and Meshorer E (2011) Fluorescence recovery after
photobleaching of chromatin proteins in embryonic stem cells. J Vis Exp. In
press.
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Badi Sri, S, Takizawa T and Meshorer E (2010) Chromatin
immunoprecipitation (ChIP) in mouse hippocampal cells and tissues. Methods Mol
Biol, In press.
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Gaspar-Maia A, Alajem A, Meshorer E and Ramalho-Santos M (2010) Open
chromatin in stem cells and pluripotency. Nat Rev Mol Cell Biol, 12(1):36-47.
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Mattout, A and Meshorer E (2010) Chromatin and nuclear architecture in
pluripotent embryonic stem cells. Curr Opin Cell Biol, 22:334-341.
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Schwartz S, Meshorer E and Ast G (2009) Chromatin organization marks
exon-intron structure. Nat Struct Mol Biol. 16:990-996 (cover).
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Gaspar-Maia A, Alajem A, Polesso F, Sridharan R, Mason MJ, Heidersbach A,
Ramalho-Santos J, McManus MT, Plath K, Meshorer E, Ramalho-Santos M (2009) Chd1
regulates open chromatin and pluripotency of embryonic stem cells. Nature, 460:
863-868.
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Raghu Ram EVS and Meshorer E (2009) Transcriptional competence in
pluripotency. Genes Dev. 23:2793-8.
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Efroni, S, Melcer S, Nissim-Rafinia M and Meshorer E (2009) Cells do play
with dice: a statistical physics view of transcription. Cell Cycle. 8:43-48.
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Prokocimer M, Davidovich M, Nissim-Rafinia M, Wiesel-Motiuk N, Bar D,
Barkan R, Meshorer E and Gruenbaum Y (2009) Nuclear lamins: key regulators of
nuclear structure and activities. J Cell Mol Med. 13:1059-1085.
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Efroni S, Duttagupta R, Cheng J, Dehghani H, Hoeppner DJ, Dash C,
Bazett-Jones DP, Le Grice S, McKay RDG, Buetow KH, Gingeras TR, Misteli T,
Meshorer E (2008) Global transcription in pluripotent embryonic stem cells.
Cell Stem Cell, 2:437-447.
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Takizawa T and Meshorer E (2008) Chromatin and nuclear architecture in the
central nervous system. Trends Neurosci. 31:343-352.
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Meshorer E and Gruenbaum Y (2008) Gone with the Wnt/Notch: stem cells in
laminopathies, progeria and aging. J Cell Biol. 181:9-13.
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Meshorer E (2008) Imaging chromatin in embryonic stem cells. StemBook,
doi/10.3824/stembook.1.2.1, http://www.stembook.org.
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Meshorer E (2007) Chromatin in embryonic stem cell neuronal
differentiation. Histol. istopathol. 22:311-319.
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Meshorer E, Yellajoshula D, George E, Scambler PJ, Brown D and Misteli T
(2006) Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic
stem cells. Dev Cell, 10:105-116.
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Meshorer E and Soreq H (2006) Virtues and woes of acetylcholinesterase
alternative splicing in stress related neuropathology. Trends Neurosci.
29:216-224.
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Meshorer E, Bryk B, Toiber D, Cohen J, Podoly E, Dori A and Soreq H (2005)
SC35 promotes sustainable stress-induced alternative splicing of neuronal
acetylcholinesterase mRNA. Mol. Psych. 10:985-997. [Lilly award winner. Cover].
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Meshorer E, Biton I, Ben-Shaul Y, Assaf Y, Soreq H and Cohen Y (2005)
Brain diffusion and transport abnormalities under cholinergic imbalance. FASEB
J. 19:910-22.
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Meshorer E, Toiber D, Zurel D, Sahly I, Dori A, Cagnano E, Schreiber L,
Grisaru D, Tronche F and Soreq H (2004) Combinatorial Complexity of 5’ Alternative
ACHE Transcripts and Protein Products. J. Biol. Chem. 279:29740-29751.
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Stoilov P, Meshorer E, Gencheva M, Glick D, Soreq H and Stamm S (2002)
Defects in pre-mRNA processing as causes of and predisposition to diseases. DNA
Cell Biol. 21:803-818
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Meshorer E and Soreq H (2002) Pre-mRNA splicing modulations in senescence.
Aging Cell 1:10-16 (Cover).
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Meshorer E, Erb C, Gazit R, Pavlovsky L, Kaufer D, Friedman A, Glick D,
Ben-Arie N and Soreq H (2002) Alternative splicing and neuritic mRNA
translocation under long-term neuronal hypersensitivity. Science, 295:508-512.
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Lev-Lehman E, Evron T, Broide RS, Meshorer E, Ariel I, Seidman S and Soreq
H (2000) Synaptogenesis and myopathy under acetylcholinesterase overexpression.
J. Mol. Neurosci. 14:93-105.
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Sigalevich P, Meshorer E, Helman Y and Cohen Y (2000) Transition from
anaerobic growth conditions of the sulfate reducing bacterium Desufovibrio
oxyclinae resulting in floculation. Appl. Environ. Microbiol. 66:5005-5012