Dr. Elias A. Said

Montreal University, Canada

Email: elias_a_said@yahoo.fr

Qualifications

2004 Ph.D., Pasteur Institute, Department of Virology, France

Publications(Selected)

1. Said E.A. The Need for New Anti-Hepatitis C Virus Therapeutic Strategies Targeting the cellular micro-ribonucleic acids? SQU Med J. 2010; 312-17; Invited article.
2. Said E.A., Zhang Y., Salah M., El-Haddad E., Shoukry N. and Sekaly R.P. HCV ssRNA stimulation of dendritic cells. In preparation. Co-first author and supervising the project.
3. Said E.A., Trautmann L., Dupuy F.P., Zhang Y., Shi Y., Hill B.J., El-Far M., Ancuta P., Boulassel M.R., Routy J.P., Douek D.C., El-Haddad E.K. and Sekaly R.P. PD-1 Induced IL10 Production by Monocytes Impairs T-cell Activation in a Reversible Fashion. Nature Medicine. 2010; 452-9.
4. Gosselin A., Monteiro P., Chomont N., Diaz-Griffero F., Said E.A. , Fonseca S., Wacleche V., El-Far M., Boulassel M.R., Routy J.P., Sekaly R.P., Ancuta P. Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T-cells are highly permissive to HIV-1 infection. Journal of Immunology. 2010; 1604-16. *Co-first author.
5. Dekaban G.A., Snir J., Shrum B., Merrill M., Said E.A., Sekaly R.P., Foster P.J., O'Connell P.J., Willert C. Semi-quantitation of mouse dendritic cell migration in vivo using cellular MRI. Journal of Immunotherapy. 2009; 240-51.
6. Gaucher D., Therrien R., Kettaf N., Angermann B.R., Boucher G., Filali-Mouhim A., Moser J.M., Mehta R.S., Drake D.R. 3rd, Castro E., Akondy R., Rinfret A., Yassine-Diab B., Said E.A., Chouikh Y., Cameron M.J., Clum R., Kelvin D., Somogyi R., Greller L.D., Balderas R.S., Wilkinson P., Pantaleo G., Tartaglia J., Haddad E.K., Sekaly R.P. Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses. Journal of Experimental Medicine. 2008; 3119-31.
7. Van Grevenynghe J., Halwani R., Chomont N., Ancuta P., Peretz Y., Tanel A., Procopio F.A., Shi Y., Said E.A., Haddad E.K., Sekaly R.P. Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection. Seminars in Immunology. 2008; 196-203.
8. El-Far M., Halwani R., Said E.A., Trautmann L., Doroudchi M., Janbazian L., Fonseca S., Van grevenynghe J., Yassine-Diab B., Sékaly R.P., Haddad E.K. T-cell exhaustion in HIV infection. Current HIV/AIDS Reports. 2008; 9 -13.
9. Van grevenynghe J., Procopio F.A., He Z., Chomont N., Riou C., Zhang Y., Gimmig S., Boucher G., Wilkinson P., Shi Y., Yassine-Diab B., Said E.A., Trautmann L., El Far M., Balderas R.S., Boulassel M.R., Routy J.P., Haddad E.K., Sekaly R.P. Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection. Nature Medicine. 2008; 266-74.