Prof. Chunfu Zheng

Chinese Academy of Sciences, China

Email: zheng.alan@hotmail.com

Qualifications

2001  Ph.D., Chongqing Medical University, China

1997  M.Sc., Fujian Medical University, China

1991  D.V.M., China Agriculture University, China

Publications (Selected)

1. Xing JJ, Wang S, Lin FS, Pan WW, Hu CD, Chunfu Zheng. A Comprehensive Characterization of Interaction Complexes of Herpes Simplex Virus Type 1 ICP22, UL3, UL4 and UL20.5. Journal of Virology. 2011; 85(4):1881-1886.
2. Cai MS, Wang S, Xing JJ, Chunfu Zheng. Characterization of the nuclear import and export signals and its subcellular transport mechanism of VZV ORF9. Journal of General Virology. 2011; 92(3):621-626.
3. Xing JJ, Wang S, Guo H, Li Y, Zhao L, Pan WW, Lin FS, Zhu HF, Wang Lei, Li ML, Wang Lin, Ni LW, Chunfu Zheng. Characterization of the Subcellular Localization of Herpes Simplex Virus Type 1 Proteins in Living Cells. Medical Microbiology and Immunology. 2011; 200(1):61-68.
4. Wu FQ, Xing JJ, Wang S, Li ML, Chunfu Zheng. Screening and identification of host factors interacting with UL14 of herpes simplex virus 1. Medical Microbiology and Immunology. 2011. In press.
5. Li ML, Wang L, Chunfu Zheng. Host cellular targets of tegument protein VP22 of herpes simplex virus 1. Archives of Virology. 2011. In press
6. Xing JJ, Wu FQ, Wang S, Krensky AM, Mody CH, Chunfu Zheng. Granulysin production and anticryptococcal activity is dependent upon a far upstream enhancer that binds STAT5 in human peripheral blood CD4+ T cells. Journal of Immunology. 2010;185(9):5074-81.
7. Xing JJ, Wu FQ, Pan WW, Chunfu Zheng. Molecular anatomy of subcellular localization of HSV-1 tegument protein US11 in living cells. Virus Research. 2010;153(1):71-81.
8. Ding Q, Guo H, Lin FS, Pan WW, Ye B, Alan C Zheng. Characterization of the Nuclear Import and Export Mechanisms of Bovine Herpesvirus-1 Infected Cell Protein 27. Virus Research.2010;149(1):95-103.
9. Shi M, Lin S, Zheng C and Mody CH. Real-time imaging of trapping and ureasedependent transmigration of Cryptococcus neoformans in mouse brain. Journal of Clinical Investigation. 2010;120(5):1683–1693.
10. Guo H, Ding Q, Lin FS, Pan WW, Lin JY, Alan C Zheng. Characterization of the Nuclear and Nucleolar Localization Signals of Bovine Herpesvirus-1 Infected Cell Protein 27. Virus Research. 2009;145:312-320.
11. Zheng CF, Gill MJ, Krensky AM, Kubes P, and Mody CH. PI3K and STAT5 Cooperate in the Regulation of Inducible Granulysin Expression in IL-2 Activated Primary CD4+ T cells and activation of these pathways is defective in HIV patients. J Immunol.2008;180(11):7221-9
12. Zheng CF, Ma L, Jones GJ, Gill MJ, Krensky AM, Kubes P, Mody CH. Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans and activation of this pathway is defective in HIV patients. Blood.  2007; 109(5): 2049-2057.
13. Zheng C, Brownlie R, Huang Y, Babiuk L and van Drunen Littel-vanDen Hurk S. Intercellular trafficking of the major tegument protein VP22 of bovine herpesvirus-1 and its application to improve a DNA vaccine. Archive Virology. 2006;151(5):985-93.
14. Zheng C, Juhls C, Oswald D, Sack F, IWestfehling I, Wittig B, Babiuk L and van Drunen Littel-van den Hurk S.   Effect of different nuclear localization sequences on the immune responses induced by a MIDGE vector encoding bovine herpesvirus-1 glycoprotein D. Vaccine. 2006; 24(21):4625-9.
15. Zheng C, Brownlie R, Babiuk L and van Drunen Littel-vanDen Hurk S. Characterization of nuclear localization and export signal of bovine herpesvirus-1 VP22. J. Virol. 2005;79(18):11864-72.
16. Zheng C, Babiuk L and van Drunen Littel-van Den Hurk S. Major tegument protein VP22 of bovine herpesvirus-1 as an enhancer for a DNA Vaccine in cattle. J. Virol. 2005; 79(3): 1948-53.
17. Zheng C, Brownlie R, Huang Y, Babiuk L and van Drunen Littel-vanDen Hurk S. Characterization of Nuclear Localization and Export Signals of the Major Tegument Protein VP8 of Bovine Herpesvirus-1. Virology. 2004; 324(2):327-39.