Prof Jean-François Beaulieu

Université de Sherbrooke, Canada

Email: Jean-Francois.Beaulieu@USherbrooke.ca

Qualifications

1985 Ph.D., Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada

1982 M.Sc., Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada

1979 B.Sc., Biology (Biochemistry/Physiology), Faculty of Sciences, Université de Sherbrooke, Canada

Publications (Selected)

1. Gagné D, Basora N, Vachon PH, Beaulieu JF (2010) Integrin-linked kinase regulates migration and proliferation of normal human intestinal crypt cells under a fibronectin-dependent mechanism.J Cell Physiol 222:387-400 (Nov2 2009 Epub ahead of print)
2. Seltana A, Basora N, Herring E, Ménard D, Beaulieu JF (2010) A co-culture system to study intestinal wound healing. Wound Repair Regen 18: 114-122
3. Benoît Y, Paré F, Francoeur C, Jean D, Tremblay E, Boudreau F, Escaffit F, Beaulieu JF (2010) Cooperation between HNF-1alpha, Cdx2 and GATA-4 in initiating an enterocytic differentiation program in a normal, human intestinal progenitor cell line, Am J Physiol-GI 298: G504-G517.(2010 Feb 4, Epub ahead of print)
4. Basora N, Tétreault M-P, Boucher MP, Herring E, Beaulieu JF (2010) Polycystin-1 is a microtubule-driven desmosomal associated component in polarized epithelial cells. Exp Cell Res. 316:1454-1464 (Epub ahead of print March 6)
5. Beaulieu JF (2010)Editorial: Alpha6 beta4 integrin in colorectal cancer. World J Gastrointestinal Pathophysiol 1:3-11.
6. Benoit YD, Larrivée JF, Groulx JF, Stankova J, Vachon PH, Beaulieu JF (2010)Integrin alpha8 beta1 confers anoikis susceptibility to human intestinal epithelial crypt cells.Biochem Biophys Res Comm 399:434-439 (Epub 2010 Aug 3)
7. Taha R, Seidman E, Mailhot G, Boudreau F, Gendron FP, Beaulieu JF, Ménard D, Delvin E, Amre D, Levy E (2100), Oxidative stress and mitochondrial functions in the intestinal Caco-2/15 cell linePLoS One 5:e1181
8. Tremblay E, Babakissa C, Ferretti E, Seidman EG, Levy E, Ménard D, Beaulieu JF, Gene expression profiles in the mid-gestation human intestine disclose greater immaturity of the colon as compared to ileum. JPGN (in press, December 2010)
9. Marcil V, Seidman E, Sinnett D, Boudreau F, Gendron FP, Beaulieu JF, Ménard D, Precourt LP, Amre D, Levy E (2010) Modification in oxidative stress, inflammation and lipoprotein assembly in response to HNF4[alpha] knockdown in intestinal epithelial cells J Biol Chem 285: 40448-40460.
10. Bustin SA, Beaulieu JF, Huggett J, Jaggi R, Kibenge SB, Olsvik PA, Penning LC, Toegel S. (2010) Editorial: MIQE précis: Practical implementation of minimum standard guidelines for fluorescence-based quantitative real-time PCR experiments. BMC Mol Biol 2010, 11:74
11. Groulx JF, Gagné D, Benoit YD, Martel D, Basora N, Beaulieu JF, Collagen VI is a basement membrane component that regulates epithelial cell-fibronectin interactions. Matrix Biology (in revision, December 2010)
12. Groulx JF, Khalfaoui T, Benoit YD, Bernatchez G, Carrier J, Basora N, Beaulieu JF, Autophagy is active in normal colon mucosa (in revision, January 2011)