Dr. Todd A. Houston

Griffith University, Australia

Email: t.houston@griffith.edu.au

Qualifications

1993    Doctor of Philosophy, Degree University of Michigan, Organic Chemistry

1987    Bachelor of Science Degree, Graceland College, Chemistry

Publications (Selected)

1. Wilkinson, B. L.; Bornaghi, L. F.; Houston, T. A.; Innocenti, A.; Vullo, D.; Supuran, C. T.; Poulsen, S.-A. “Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzene sulfonamides” Bioorg. Med. Chem. Lett. 2007, 17, 987.
2. Wilkinson, B. L.; Bornaghi, L. F.; Wright, A. D.; Houston, T. A.; Poulsen, S.-A. “Antimycobacterial Activity of a Bis-Sulfonamide” Bioorg. Med. Chem. Lett. 2007, 17, 1355.
3. Quader, S.; Boyd, S. E.; Jenkins, I. D.; Houston, T. A. “Multisite Modification of Neomycin B: A Combined Mitsunobu and Click Chemistry Approach” J. Org. Chem. 2007, 72, 1962.
4. Wilkinson, B. L.; Bornaghi, L. F.; Houston, T. A.; Innocenti, A.; Vullo, D.; Supuran, C. T.; Poulsen, S.-A. “Carbonic anhydrase inhibitors: inhibition of isozymes I, II and IX with triazole-linked O-glycosides of benzene sulfonamides” J. Med. Chem. 2007, 50, 1651.
5. Gray, Jr., C. W.; Barry, K.; Lindberg, E. J.; Houston, T. A. “Synthesis of an Azacrown Template for Phosphatidylinositol-4,5-Bis(phosphate) Recognition” Tetrahedron Lett. 2007, 48, 2683.
6. Quader, S.; Boyd, S. E.; Jenkins, I. D.; Houston, T. A. “Reactions of Neomycin B Under Mitsunobu Conditions. A Correction of the Literature.” Synth. Commun. 2007, 1473.
7. Houston, T. A. “Painting the Target Around the Arrow: Two-Step Prodrug Therapies from a Carbohydrate Chemist’s Perspective” Curr. Drug Delivery 2007, 4, 264.
8. Houston, T. A.; Levonis, S. M.; Kiefel, -Hydroxycarboxylic Acid Interactions in Sensing andaM. J. “Tapping into Boron/ Catalysis” Aust. J. Chem. 2007, 60, 811. [Special Issue on Organoboranes]
9. Levonis, S. M.; Bornaghi, L. F.; Houston, T. A. “Selective Monoesterification of Malonic Acid Catalyzed by Boric Acid” Aust. J. Chem. 2007, 60, 821. [Special Issue on Organoboranes]
10. Duggan, P. J.; Houston, T. A.; Kiefel, M. J.; Levonis, S. M.; Smith, B. D.; Szydzik, M. L. “Enhanced Fructose, Glucose and Lactose Transport Promoted by a 2-(Aminomethyl)phenylboronic Acid” Tetrahedron 2008, 64, 7122.
11. Houston, T. A.; Quader, S.; Boyd, S. E.; Jenkins, I. D.; -Azido-5-cholestene” Acta Cryst. 2008, E64, o1738.aHealy, P. C. “3
12. Levonis, S. M.; Kiefel, M. J.; Houston, T. A. “Boronolectin with Divergent Fluorescent Response Specific for Free Sialic Acid” Chem. Commun. 2009, 2278. (Invited Paper)
13. Houston, T. A.; Koreeda, M. “Iodine-promoted Ribosylation Leads to a Facile Acetonide-forming Reaction” Carbohydr. Res. 2009, 344, 2240.
14. Levonis, S. M.; Kiefel, M. J.; Houston, T. A.; Healy, P. C. “2’-Propynyl 2-hydroxybenzoate” Acta Cryst. 2010, E66, o226.
15. Houston, T. A. “Developing High-Affinity Boron-Based Receptors for Cell-Surface Carbohydrates” ChemBioChem 2010, 11, 954. (Invited Highlight Article)
16. Wilkinson, B. L.; Bornaghi, L. F.; Lopez, M.; Poulsen, S.-A.; Healy, P. C.; Houston, T. A.;   “Synthesis of N-Propargyl Azasugar Scaffolds for Diverse Compound Library Generation using Click Chemistry” Aust. J. Chem. 2010, 63, 821.