Dr. Pere Domingo
Autonomous Unversity of Barcelona, Spain
Email: pdomingo@santpau.cat
Qualifications
1992 Ph.D., Universitat Autònoma de Barcelona,
Spain
1979 M.D., Universidad de Barcelona, Spain
1973 B.S., Universidad de Barcelona, Spain
Publications (Selected)
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Podzamczer D, Miró JM, Bolao F, Cosín J, Sirera G,
Domingo P, Laguna F, Santamaría J, Verdejo J, and the Spanish Toxoplasmosis
Study Group. Twice-weekly versus daily maintenance therapy with
sulfadiazine-pyrimethamine for toxoplasmic encephalitis in AIDS patients. Ann
Intern Med 1995; 123: 175-180.
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López-Navidad A, Domingo P, Caballero F, González C,
Santiago C. Successful transplantation of organs retrieved from donors with
bacterial meningitis. Transplantation 1997; 64: 365-368.
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Barquet N, Domingo P, Caylà JA, González J, Rodrigo C,
Fernández-Viladrich P, Moraga-Llop FA, Marco F, Vázquez J, Sáez-Nieto JA, Casal
J, Canela J, Foz M,for the Barcelona Meningococcal Disease Study Group.
Prognostic factors in meningococcal disease. Development of a bedside
predictive model and scoring system. JAMA 1997; 278: 491-496.
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Domingo P, Barquet N, Alvarez M, Coll P, Nava J, Garau J.
Group B streptococcal meningitis in adults. Report of twelve cases and review.
Clin Infect Dis 1997; 25: 1180-1187.
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Domingo P, Fontanet A, Sánchez F, Allende L, Vazquez G.
Morbidity associated with long-term use of totally implantable ports in
patients with AIDS. Clin Infect Dis 1999; 29: 346-351.
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Barquet N, Domingo P, Caylà JA, González J, Rodrigo C,
Fernández-Viladrich P, Moraga-Llop FA, Marco F, Vázquez J, Sáez-Nieto JA, Casal
J, Canela J, Foz M, and the Barcelona Meningococcal Disease Study Group.
Meningococcal disease in a large urban population: predictors of dismal
prognosis. Arch Intern Med 1999; 159: 2329-2340.
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Domingo P, Matias-Guiu X, Pujol RM, Francia E, Sambeat
MA, Vazquez G. Subcutaneous adipocyte apoptosis in HIV-1-protease
inhibitor-associated lipodystrophy. AIDS 1999; 13: 2261-2267.
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López JC, Miró JM, Peña JM, Podzamczer D, Alberdi JC,
Claramonte X, Cosín J, Martínez E, Gonzalez J, Domingo P, et al.
Discontinuation of primary and secondary Pneumocystis carinii prophylaxis is
safe in HIV-infected patients after immunological restoration with HAART.
Results of an open, randomized and multicentric clinical trial (GESIDA 04/98).
N Engl J Med 2001; 344: 159-167.
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Domingo P, Torres OH, Ris J, Vazquez G. Herpes zoster as
an immune reconstitution disease following initiation of highly active
antiretroviral therapy in HIV-1 infected patients. Am J Med 2001; 110: 605-609.
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Domingo P, Matias-Guiu X, Pujol RM, Domingo JC, Arroyo
JA, Sambeat MA, Vazquez G. Switching to nevirapine decreases insulin levels but
does not improve subcutaneous adipocyte apoptosis. J Infect Dis 2001; 184:
1197-1201.
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Martínez E, Arnaiz JA, Podzamczer D, Dalmau D, Ribera E,
Domingo P, Knobel H, Riera M, Pedrol E, Force Ll, Segura F, Richart C,
Cortes C, Javaloyas M, Aranda M, Gatell JM. Switching from protease
inhibitors to nevirapine, efavirenz or abacavir: a randomized, multicenter,
open-label simplification trial in successfully treated HIV-1-infected
patients. N Engl J Med 2003; 349: 1036-1046.
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Martínez-Picado J, Negredo E, Ruiz L, Shintani A, Fumaz
CR, Zala C, Domingo P, Vilaró J, Llibre JM, Viciana P, Hertogs K, Boucher C,
D'Aquila RT, Clotet B, and the SWATCH Study Team. Alternation of antiretroviral
drug regimens for HIV infection: a randomized trial. Ann Intern Med 2003;139:
81-89.
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Domingo P, Labarga P, Palacios R, Fernández-Guerrero M,
Terrón JA, Pérez-Elias MJ, et al. Dyslipidaemia improvement in patients
switching from stavudine to tenofovir: preliminary results from the Recover
Study. AIDS 2004; 18: 1475-1478.
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Domingo P, Vidal F, Domingo JC, Veloso S, Sambeat MA,
Torres F, Sirvent J, Vendrell J, Matias-Guiu X, Richart C. Tumor necrosis
factor alpha in fat redistribution syndromes associated with combination
antiretroviral therapy: its role in subcutaneous adipocyte apoptosis. Eur J
Clin Invest 2005 ; 35 : 771-780.
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Giralt M, Domingo P, Guallar JP, Rodriguez ML, Alegre M,
Domingo JC, Villarroya F. Human immunodeficiency virus type 1
(HIV-1) infection alters gene expression in adipose tissue, contributing to
HIV/highly active antiretroviral therapy-associated lipodystrophy. Antivir Ther
2006; 11: 729-740.
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Moreno-Torres A, Domingo P, Pujol R, Blanco F, Arroyo JA,
Sambeat MA. Liver fat content in HIV-1-infected patients on combination
antiretroviral therapy: correlation with metabolic alterations. Antivir Ther
2007; 12: 195-203.
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Domingo P, Suárez-Lozano I, Torres F, Teira R,
Lopez-Aldeguer J, Vidal F, Muñoz A, Viciana P, Lozano F, Vergara A, Roca B,
García Alcalde ML, Cosín J, Terrón A, Galindo MJ,Geijo P, Ribera E,
Gonzalez J, Sanchez T, Lacalle JR, Garrido M. First-line antiretroviral therapy
with efavirenz or lopinavir/ritonavir plus two nucleoside analogues: the SUSKA
Study, a non-randomized comparison from the VACH Cohort. J Antimicrob Chemother
2008; 61: 1348-1358.
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Domingo P, Suarez-Lozano I, Torres F, Pomar V, Ribera E,
Galindo MJ, Cosin J, Garcia-Alcalde ML, Vidal F, Lopez-Aldeguer J, Roca B,
Gonzalez J, Lozano F, Garrido M, the VACH Cohort Study Group. Bacterial
meningitis in HIV-1-infected patients in the era of highly active
antiretroviral therapy. J Acquir Immune Defic Syndr 2009; 51: 582-587.
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Domingo P, Cabeza MC, Pruvost A, Salazar J, Gutierrez MM,
Mateo MG, Domingo JC, Fernandez I, Villarroya F, Muñoz J, Vidal F, Baiget M.
Relationship between HIV/highly active antiretroviral therapy
(HAART)-associated lipodystrophy syndrome and stavudine triphosphate
intracellular levels in patients with stavudine-based antiretroviral regimes.
Clin Infect Dis 2010; 50: 1033-1040.
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Domingo P, Gallego-Escuredo JM, Domingo JC, Gutierrez MM,
Mateo MG, Fernandez I, Vidal F, Giralt M, Villarroya F. Serum FGF21 levels are
elevated in association with lipodystrophy, insulin resistance and biomarkers
of liver injury in HIV-1-infected patients. AIDS 2010; 24: 2629-2637.
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Domingo P, Torres-Torronteras J, Pomar V, Giralt M,
Domingo JC, Gutierrez MM, Gallego-Escuredo JM, Mateo MG, Cano-Soldado P,
Fernandez I, Pastor-Anglada M, Vidal F, Villarroya F, Andreu A, Marti R.
Uridine metabolism in HIV-1-infected patients: the role of infection, highly
active antiretroviral therapy (HAART) and the development of
HIV-1/HAART-associated lipodystrophy syndrome (HALS). PLOs One 2010; 5: e13896.
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Domingo P, Cabeza MC, Pruvost A, Salazar J, Gutierrez MM,
Paré L, Mateo MG, Muñoz J, Domingo JC, Fernández I, Villarroya F, Vidal F,
Baiget M. Association of thymidylate synthase polymorphisms with stavudine
triphosphate intracellular levels and lipodystrophy. Antimicrob Agents
Chemother 2011; 55: 1428-143.