Prof. Elena Markvicheva

Russian Academy of Sciences, Russia



1992  Ph.D., Shemykin-Ovchinnikov Inst of Bioorganic Chem., Russia

1982  M.Sc., Mendeleev University of Chemical Technology of Russia, Russia

Publications (Selected)

  1. Poncelet D. and Markvicheva E., Microencapsuation and alginate, In: Micro-encapsulation of Food Ingredients, Per Vilstrup (Ed.), Leatherhead Publishing Food RA: London, 2001, pp. 215-223.
  2. Markvicheva E and Grandfils Ch., Microcarriers for animal cell culture, In: Fundamentals of Cell Immobilisation Biotechnology, Series Focus on Biotechnology, Willaert R., Nedovich V. (Eds) Kluwer Academic Publishers: Dordrecht-Boston-London, 2004, v. 8A, pp. 441-461.
  3. Markvicheva E, Dugina T., Grandfils Ch., Lange M., Stashevskaya K., Vasilieva T., Rumsh L., Strukova S., Application of bioencapsulated proteinases and peptides for wound healing, Charter 12, In: Advanced Biomaterials for Medical Applications, Series II Mathematics, Physics and Chemistry, Thomas D.W. (Ed.), Kluwer Academic Publishers: Dordrecht-Boston-London, 2004, pp. 165-176.
  4. Marc A., Markvicheva E., Jourdain C., Bezdetnaya L., Merlin J-L., Guillemin. F., Zubov V., Goergen, J-L., Spheroids formation by encapsulation of cancer cells to mimic small size tumors, In: Animal Cell Technology meets Genomics, Godia F. and Fussenger M. (Eds.), Springer, Netherlands, 2005, pp. 261-263.
  5. Markvicheva E., Bioencapsulation in polymer micro- and nanocarriers and applications in biomedical fields, Chapter 30, In: Finely dispersed particles: micro-, nano-, and atto-engineering, Spasic A., Hsu J-P (Eds), CRC Taylor and Francis Group, New-York, 2005, pp. 853-868.
  6. Markvicheva E., Vikhrov A., Khaidukov S., Sukhacheva E., Markvichev N., Zubov V., The effect of low -intensity ultrasound on hybridoma cell proliferation and monoclonal antibody production in hollow fiber bioreactor, Annual Meeting of the Deutsche Gesellschaft fuer Zellbiologie (Hamburg, March 24-28, 1996), Eur. J. Cell Biol., 1996, v.69, Suppl. 42, pp.155-156.
  7. Vikhrov A.A., Markvicheva E.А., Mareeva T.Yu., Khaidukov S.V., Nesmeyanov V.A., Manakov M.N., Goergen J-L, Marc A., and Zubov V.P., Preparation of pure monoclonal antibody to interleukin-2 by cultivation of hybridoma cells entrapped in novel composite hydrogel beads, Biotechnol. Techn., 1998, v. 12, (1), pp. 11-14.
  8. Tahrat, H.; Chenu, S.; Benslimane, C.; Auge, C.; Malleron, A.; Cerutti, M.; Markvicheva, E.; Goergen, J. L.; Marc, A., Human fucosyltransferase production in bioreactor for the synthesis of therapeutic oligosaccharides, Recents Prog. Genie Procedes 1999, v. 13 (71), pp. 319-326 (in French).
  9. Markvicheva E.A, Kuptsova S.V., Mareeva T.Yu, Vikhrov A.A., Dugina T.N., Strukova S.M., Belokon Yu.N., Kochetkov K.A., Baranova E.N., Zubov V.P., Poncelet D., Rumsh L.D., Immobilized enzymes and cells in poly(N-vinyl caprolactam)-based hydrogels: preparation, properties and applications in biotechnology and medicine, Appl. Biochem. Biotechnol., 2000, v. 88 (1-3), pp. 145-157.
  10. Kuptsova S., Markvicheva E., Kochetkov K., Belokon' Yu.,Rumsh L, and Zubov V., Proteases entrapped in hydrogels based on poly(N-vinyl caprolactam) as promising biocatalysts in water-organic systems, Biocatalysis and Biotransformations, 2000, v. 18, pp. 133-149.
  11. Vilchez C., Garbayo I., Markvicheva E., Galvan F., Leon R., Studies on the suitability of alginate-entrapped Chlamydomonas reihardtii cells for sustaining nitrate consumption process, Bioresource Technology, 2001, v.78, pp. 55-61.
  12. Markvicheva E., Bezdetnaya L., Bartkowiak A., Marc A., Goergen J-L, Guillemin F., Poncelet D., Encapsulated multicellular tumor spheroids a a novel model to study small size tumors, Chem. Industry, 2003, v. 57 (12), pp. 585-588.
  13. Markvicheva E., Grandfils, Ch., Bezdetnaya. L., Goergen J-L., Bartkowiak A, Guillemin F., Poncelet D., Bioencapsulated peptides, proteins, animal cells: preparation and applications in biomedical fields, Chem. Industry, 2004, v.58 (6a), pp. 75-78.
  14. Markvicheva E., Bioencapsulated mammalian cells, proteins, peptides: preparation and application for biomedical fields, European Journal of Cell Biology, 2004, v. 83, Suppl.54, pp. 96-97.
  15. Markvicheva E., Lozinsky V., Plieva F., Kochetkov K., Rumsh L., Zubov V., Kumar R., Parmar V., Belokon Yu., Gel-immobilized enzymes as promising biocatalysts for enantioselective hydrolysis in water/organic media, Pure and Applied Chemistry, 2005, v. 77 (1), pp. 227-236.
  16. Markvicheva E., Stashevskaya K., Strukova S., Prudchenko I., Rusanova A. Makarova A., Vasilieva T, Bespalova J., and Grandfils Ch., Biodegradable microparticles loaded with thrombin receptor agonist peptide for gastric ulcer treatment in rats, J. Drug Del. Sci. Tech, 2006, v 16(4), pp.321-325.
  17. E. Markvicheva, K. Stashevskaya, S. Strukova, I. Prudchenko, A. Rusanova, A. Makarova, T. Vasilieva, J. Bespalova, Ch. Grandfils. Biodegradable microparticles loaded with thrombin receptor agonist peptide for gastric ulcer treatment in rats. J. Drug Del. Sci. Tech. 2006, 16(4), pp. 321-325.
  18. Stashevskaya K, Markvicheva E, Strukova S, Prudchenko I, Zubov V, Grandfils Ch. Thrombin receptor agonist peptide entrapped in poly(d, l)-lactide-co-glycolide microparticles: preparation and characterization. J. Microencapsulation, 2007 v. 24(2), pp. 129-142.
  19. Borodina T., Markvicheva E., Kunizhev S., Möhwald H., Sukhorukov G., Kreft O. Controlled release of DNA from self-degrading microcapsules. Macromol. Rapid Commun., 2007, 28, pp. 1894-1899.
  20. Popov V.K., Antonov E.N., Bagratashvili V.N., Bochkova S.A., Bukharova T.B., Fatkhutdinov,T.H., Markvicheva E.A., Popova A.V., Rumsh L.D., Volkov A.V., Surface Selective Laser Processing: A New Methodology to Work with Thermolable Polymer Particles, Regenerative Medicine, 2009, 4 (6), pp. S253-254.
  21. Selina O. E., Belov S. Yu. Vlasova N. N. Balysheva V. I. Churin A. I. Bartkowiak A., Sukhorukov G.B., Markvicheva E.A., Biodegradable microparticles with entrapped DNA for development of new DNA vaccines, Russian Journal of Bioorganic Chemistry, 2009, v 35 (1), pp. 103–110 (in Eng).
  22. Tsoy A.M., Zaytseva-Zotova D.S., Edelweiss E.F., Bartkowiak A., Goergen J-L., Vodovozova E.L. and Markvicheva E.A. Microencapsulated multicellular tumor spheroids: preparation and use as a novel in vitro model for drug screening Biochemistry (Moscow) Supplement Series B Biomedical Chemistry 2010, v 4 (3), pp. 243-250 (in Eng).
  23. Zaytseva-Zotova D., Balysheva V., Tsoy A., Drozdova M., Akopova T., Vladimirov L., Chevalot I., Marc A., Goergen J.-L., Markvicheva E. Biocompatible Smart Microcapsules Based on Chitosan-Poly(Vinyl Alcohol) Copolymers for Cultivation of Animal Cells, Advanced Engineering Materials, 2011, v 13 (12), pp. B493-500.
  24. Zaytseva-Zotova D., Udartseva O., Andreeva E., Bartkowiak A., Bezdetnaya L.,Guillemin F., Goergen J.-L., Markvicheva E. Polyelectrolyte microcapsules with entrapped multicellular tumor spheroids as a novel tool to study the effects of photodynamic therapy, Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2011, v. 97B (2), pp. 255–262.
  25. Borodina T., Grigoriev D., Markvicheva E., Mohwald H., Shchukin D. Vitamin E Microspheres Embedded Within a Biocompatible Film for Planar Delivery, Advanced Engineering Materials, 2011, 13 (3), pp. B123–B130.
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