Dr. Yifan Zhan
Immunology Division
The Walter and Eliza Hall Institute of Medical Research, Australia
Email: zhan@wehi.edu.au
Qualifications
1994 Ph.D., Department of Microbiology, Melbourne University, Australia
1987 Master of Medical Science, China
1983 Bachelor of Medical Science, China
Publications (selected)
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Hao, S., Zhu, X., Huang, Z., Yang, Q., Liu, H., Wu, Y., Zhan, Y., Dong, Y., Li, C., Wang, H., Haasdijk, E., Wu, Z., Li, S., Yan, H., Zhu, L., Guo, S., Wang, Z., Ye, A., Lin, Y., Cui, L., … Liu, C. (2024). Cross-species single-cell spatial transcriptomic atlases of the cerebellar cortex. Science (New York, N.Y.), 385(6716), eado3927. https://doi.org/10.1126/science.ado3927
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Ruan, X., Huang, D., Zhan, Y., Huang, J., Huang, J., Ng, A. T., Tsu, J. H., & Na, R. (2023). Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study. eLife, 12, e86379. https://doi.org/10.7554/eLife.86379
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Zhao, J., Li, L., Feng, X., Gao, C., Gao, L., Zhan, Y., Wang, Z., Zhao, M., Yin, H., & Lu, Q. (2023). TIGIT-Fc fusion protein alleviates murine lupus nephritis through the regulation of SPI-B-PAX5-XBP1 axis-mediated B-cell differentiation. Journal of autoimmunity, 139, 103087. https://doi.org/10.1016/j.jaut.2023.103087
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Zhang, W., Wang, L., Sun, X. H., Liu, X., Xiao, Y., Zhang, J., Wang, T., Chen, H., Zhan, Y. Q., Yu, M., Ge, C. H., Li, C. Y., Ren, G. M., Yin, R. H., & Yang, X. M. (2021). Toll-like receptor 5-mediated signaling enhances liver regeneration in mice. Military Medical Research, 8(1), 16. https://doi.org/10.1186/s40779-021-00309-4
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Wang, L. Y., Cui, J. J., Ouyang, Q. Y., Zhan, Y., Guo, C. X., & Yin, J. Y. (2020). Remdesivir and COVID-19. Lancet (London, England), 396(10256), 953–954. https://doi.org/10.1016/S0140-6736(20)32019-5
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Dong, R., Yang, R., Zhan, Y., Lai, H. D., Ye, C. J., Yao, X. Y., Luo, W. Q., Cheng, X. M., Miao, J. J., Wang, J. F., Liu, B. H., Liu, X. Q., Xie, L. L., Li, Y., Zhang, M., Chen, L., Song, W. C., Qian, W., Gao, W. Q., Tang, Y. H., … Wang, J. (2020). Single-Cell Characterization of Malignant Phenotypes and Developmental Trajectories of Adrenal Neuroblastoma. Cancer cell, 38(5), 716–733.e6. https://doi.org/10.1016/j.ccell.2020.08.014
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Yan, Y., Zhan, Y., Wang, X., & Hou, J. (2020). Clinical evaluation of ultrasonic subgingival debridement versus ultrasonic subgingival scaling combined with manual root planing in the treatment of periodontitis: study protocol for a randomized controlled trial. Trials, 21(1), 113. https://doi.org/10.1186/s13063-019-4031-y
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Liu, C., Baffoe, D. K., Zhan, Y., Zhang, M., Li, Y., & Zhang, G. (2019). Halophile, an essential platform for bioproduction. Journal of microbiological methods, 166, 105704. https://doi.org/10.1016/j.mimet.2019.105704
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Chang, L., Zhan, Y., & Liu, C. (2018). Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 34(4), 501–509. https://doi.org/10.13345/j.cjb.170267
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Allan RS, J Waithman , S Bedoui , CM Jones, JA Villadangos, YF Zhan, AM Lew, K Shortman, WR Heath, FR Carbone. Migratory Dendritic cells transfer antigen to a lymph node-resident dendritic cell population for efficient CTL priming. Immunity. 25:153, 2006.(IF=19.23; C=132)
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LimB, RM Sutherland, YF Zhan, G Deliyannis, LE Brown and AM Lew Targeting CD45RB alters T cell migration and delays viral clearance. Int Immunol. 18:291, 2006(IF=3.31, C=4)
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Londrigan SL, RM. Sutherland, JL. Brady, YF Zhan, R Li, E Estella, TWH. Kay and AM. Lew. Prolonged local expression of anti-CD4 antibody by adenovirally transduced allografts can promote long-term graft survival: Anti-CD4 antibody enhances graft survival J Gen Med 8:42, 2006(IF=3.70; C=7)
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Corbett AJ., I Caminschi, BS McKenzie, JL. Brady, MD Wright, PL Mottram, PM Hogarth, AN Hodder, YF Zhan, DM. Tarlinton, K Shortman and AM. Lew Antigen delivery via two molecules on the CD8-dendritic cell subset induces humoral immunity in the absence of conventional “danger” Eur J Immunol 35:2815, 2005 (IF=4.66;C=26)
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Uldrich AP, NY Crowe, K Kyparissoudis, DG Pellicci, YF Zhan, AM Lew, P Bouillet, A Strasser, MJ Smyth, DI Godfrey. NKT cell stimulation with glycolipid antigen in vivo:co-stimulation-dependent expansion, Bim-dependent contraction, and hypo-responsiveness to further antigenic challenge. J Immunol 175:3092, 2005 (IF=6.07;C=47)
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Zhan YF, D Funda, A L. Every, P Funda, JF. Purton, TJ. Cole, DI. Godfrey, J L. Brady, SI. Mannering, LC. Harrison, AM. Lew. GITR upregulation by glucocorticoid-receptor-dependent and -independent pathways is associated with different T-cell fates.Int Immunol16:1315-21, 2004 (IF=3.31;C=13)
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Villunger A, VS Marsden, YF Zhan, M Erlacher, AM Lew, P Bouillet, S Berzins, DI Godfrey, WR Heath and A Strasser TCR/CD3 Ligation Induced Apoptosis of Semi-Mature CD4+8-HSA+Thymocytes Requires the BH3-Only Bcl-2 Family Member Bim, Uses the Apaf-1/Caspase-9 Apoptosome as an Amplifier but is Independent of Death Receptor Signaling PNAS 101:7052-7057, 2004. (IF=9.60;C=38)
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ZhanYF, L E. Brown, G Deliyannis, S Seah, OL. Wijburg, J Price, R A. Strugnell, PJ. O’Connell and AM LewResponses against complex antigens in various models of CD4 T-cell deficiency: surprises from an anti-CD4 antibody transgenic mouse. Immunol Res 30:1-14, 2004 (IF=2.1;C=5)
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Dyer C, YF Zhan, JL Brady, FR Carbone, MJ Smyth, and AM Lew Unexpectedly, induction of cytotoxic T lymphocytes enhanced the humoral response after DNA immunization Blood103:3073-5, 2004. (IF=10.90;C=3)
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Street SEA, Y Hayakawa, J Tanner, YF Zhan, AM Lew, D MacGregor, D Raulet, A Diefenbach, H Yagita, DI Godfrey, and MJ. Smyth. Innate immune surveillance of spontaneous lymphomas of B cell origin. J Exp Med199:879-884, 2004. (IF=15.61;C=74)
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Zhan YF, JL Brady, W Irawaty, HE. Thomas, TW. Kay and AM. Lew. Activated macrophages require T cells for xenograft rejection under the kidney capsule Immunol Cell Biol 81:451-458, 2003 (IF=3.033;C=6)
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Zhan, YF, JF Purton, DI. Godfrey, TJ Cole, WR Heath and AM. Lew. Cell-autonomous antigen-induced thymic deletion is predominantly mediated in a cohort of double positive cells without classical activation. PNAS 100:1197-1202, 2003. (IF=10.3;C=18)
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Purton JF, YF Zhan, DR Liddicoat, CL Hardy, AM Lew, TJ Cole and DI Godfrey Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice Eur J Immunol. 32:3546-3555, 2002. (IF=4.66;C=21)
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Robyn M. Sutherland, B S. McKenzie, YF Zhan, Alexandra J. Corbett, Annette Fox-Marsh, Harry M. Georgiou, Leonard C. Harrisonand Andrew M. Lew. Anti-CD45RB antibody deters xenograft rejection by modulating T cell priming and homing Int Immunol 14 953-962, 2002.(IF=3.31; C=14)
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Zhan YF, JL Brady, RM Sutherland and AM Lew Without CD4 help, CD8 rejection of pig xenografts requires CD28 costimulation but not perforin killing J Immunol 167: 6279-6285, 2001 (IF=6.48;C=20)
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McKenzie AW, Geogiou HM, Zhan YF, Brady JL and Lew AM.Protection of xenografts by a combination of immunoisolation and a single dose of anti-CD4 antibody. Cell Transplant 10:183-93, 2001 (IF=3.48; C=10)
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Zhan YF, Corbett AJ, Brady JL, Sutherland RM, and Lew AM. CD4 help independent-induction of cytotoxic CD8 cells to allogeneic P815 tumour cells is absolutely dependent on costimulation. J Immunol 165:3612-3619, 2000.(IF=6.48;C=42)
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Mottram PL, Murray-Segal LJ, Han WR, Zhan YF, Brady, JL and Lew AM Transgenic anti-CD4 antibody expression by mouse segmental pancreas allografts promotes long term survival. Transplant Immunol. 8:203-209, 2000. (IF=2.13, C=1)
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Kamath AT, Pooley J, O’Keefe MA, Vremec D, Zhan YF, Lew AM, D’Amico A, Wu L, and Shortman K The Development, maturation and Turnover rate of Mouse Spleen Dendritic Cell populations. J Immunol 165:6762-70, 2000. (IF=6.48;C=211)
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Zhan YF, Kelso A, Cheers C. Cytokine production in the murine response to brucella infection or immunization with antigenic extracts. Immunology 80:458-464, 1993 (IF=3.51; C=36)
Profile Details
https://www.researchgate.net/profile/Yifan-Zhan
https://loop.frontiersin.org/people/400822/overview