Dr. Adalberto Merighi
University of Torino, Canada



1991-1999 Associate Professor, University of Torino, Canada

1991-1993 Research Fellow, Harvard Medical School, Canada

1986-1991 Assistant Professor, University of Torino, Canada

Publications (Selected)

  1. Bencivinni I, Ferrini F, Salio C, Beltramo M, Merighi A. The somatostatin analogue octreotide inhibits capsaicin-mediated activation of nociceptive primary afferent fibres in spinal cord lamina II (substantia gelatinosa). Eur J Pain. 2010 Nov 23. [Epub ahead of print] PubMed PMID: 21109472.
  2. Lossi L, Gambino G, Salio C, Merighi A. Autophagy regulates the post-translational cleavage of BCL-2 and promotes neuronal survival. ScientificWorldJournal. 2010 May 18;10:924-9. Review. PubMed PMID: 20495771.
  3. Ferrini F, Salio C, Lossi L, Gambino G, Merighi A. Modulation of inhibitory neurotransmission by the vanilloid receptor type 1 (TRPV1) in organotypically cultured mouse substantia gelatinosa neurons. Pain. 2010 Jul; 150(1):128-40. Epub 2010 May 6. PubMed PMID: 20451324.
  4. Amritraj A, Peake K, Kodam A, Salio C, Merighi A, Vance JE, Kar S. Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice. Am J Pathol. 2009 Dec; 175(6):2540-56. Epub 2009 Nov 5. PubMed PMID: 19893049; PubMed Central PMCID: PMC2789601.
  5. Ferrini F, Salio C, Lossi L, Merighi A. Ghrelin in central neurons. Curr Neuropharmacol. 2009 Mar;7(1):37-49. PubMed PMID: 19721816; PubMed Central PMCID: PMC2724662.
  6. Lossi L, Gambino G, Ferrini F, Alasia S, Merighi A. Posttranslational regulation of BCL2 levels in cerebellar granule cells: A mechanism of neuronal survival. Dev Neurobiol. 2009 Nov;69(13):855-70. PubMed PMID: 19672954.
  7. Lossi L, Alasia S, Salio C, Merighi A. Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS. Prog Neurobiol. 2009 Aug;88(4):221-45. Epub 2009 Jan 24. Review. PubMed PMID: 19552996.
  8. Merighi A, Salio C, Ghirri A, Lossi L, Ferrini F, Betelli C, Bardoni R. BDNF as a pain modulator. Prog Neurobiol. 2008 Jul; 85(3):297-317. Epub 2008 Apr 26. Review. PubMed PMID: 18514997.
  9. Vergnano AM, Ferrini F, Salio C, Lossi L, Baratta M, Merighi A. The gastrointestinal hormone ghrelin modulates inhibitory neurotransmission in deep laminae of mouse spinal cord dorsal horn. Endocrinology. 2008 May;149 (5):2306-12. Epub 2008 Jan 17. PubMed PMID: 18202139.
  10. Merighi A, Bardoni R, Salio C, Lossi L, Ferrini F, Prandini M, Zonta M, Gustincich S, Carmignoto G. Presynaptic functional trkB receptors mediate the release of excitatory neurotransmitters from primary afferent terminals in lamina II (substantia gelatinosa) of postnatal rat spinal cord. Dev Neurobiol. 2008 Mar; 68(4):457-75. PubMed PMID: 18172890.
  11. Bardoni R, Ghirri A, Salio C, Prandini M, Merighi A. BDNF-mediated modulation of GABA and glycine release in dorsal horn lamina II from postnatal rats. Dev Neurobiol. 2007 Jun; 67(7):960-75. PubMed PMID: 17506495.
  12. Salio C, Averill S, Priestley JV, Merighi A. Costorage of BDNF and neuropeptides within individual dense-core vesicles in central and peripheral neurons. Dev Neurobiol. 2007 Feb 15; 67(3):326-38. PubMed PMID: 17443791.
  13. Ferrini F, Salio C, Vergnano AM, Merighi A. Vanilloid receptor-1 (TRPV1)-dependent activation of inhibitory neurotransmission in spinal substantia gelatinosa neurons of mouse. Pain. 2007 May; 129(1-2):195-209. Epub 2007 Feb 20. PubMed PMID: 17317009.
  14. Salio C, Lossi L, Ferrini F, Merighi A. Neuropeptides as synaptic transmitters. Cell Tissue Res. 2006 Nov;326(2):583-98. Epub 2006 Jul 18. Review. PubMed PMID: 16847638.
  15. Salio C, Lossi L, Ferrini F, Merighi A. Ultrastructural evidence for a pre- and postsynaptic localization of full-length trkB receptors in substantia gelatinosa (lamina II) of rat and mouse spinal cord. Eur J Neurosci. 2005 Oct; 22(8):1951-66. PubMed PMID: 16262634.
  16. Lossi L, Cantile C, Tamagno I, Merighi A. Apoptosis in the mammalian CNS: Lessons from animal models. Vet J. 2005 Jul; 170(1):52-66. Review. PubMed PMID: 15993789.

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