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Dr. Guoqiang Yu

University of Kentucky, USA






2000 Ph.D., Tianjin University of China, Biomedical Engineering


Publications (Selected)

  1. G. Yu, T. Durduran, C. Zhou, R. Cheng, A. G. Yodh, “Near-infrared diffuse correlation spectroscopy (DCS) for assessment of tissue blood flow,” Handbook of Biomedical Optics, In press (2010)
  2. Y. Shang, T. B. Symons, T. Durduran, A. G. Yodh, G. Yu, "Effects of muscle fiber motion on diffuse correlation spectroscopy blood flow measurements during exercise," Biomed. Opt. Express 1, 500-511 (2010)
  3. T. M. Busch, H. W. Wang, E. P Wileyto, G. Yu, R. M. Bunte, “Increasing damage to tumor blood vessels during vascular-targeting PDT through use of low fluence rate,” Radiation Research 0033-7587/10 (2010)
  4. T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, W. J. Gaynor, T. L. Spray,
  5. S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht. “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” Journal of Biomedical Optics 15(3):037004 (2010)
  6. M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine,
  7. A. G. Yodh, J. A. Detre, and W. A. Kofke, "Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared diffuse correlation spectroscopies in critically brain-injured adults," Neurocrit Care 12(2): 173-180 (2010)
  8. Y. Shang, Y. Zhao, R. Cheng, L. Dong, D. Irwin, and G. Yu, “Portable optical tissue flow oximeter based on diffuse correlation spectroscopy,” Opt Lett 34(22), 3556-3558 (2009)
  9. T. M. Busch, X. Xing, G. Yu, A. G. Yodh, E. P. Wileyto, H. W. Wang, T. Durduran, T. C. Zhu,
  10. K. K.H. Wang, “Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to photofrin photodynamic therapy,” Photochem. Photobiol. Sci.  8: 1683-1693 (2009)
  11.  C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J Biomed Opt 14(3):034015 (2009)
  12. Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, "Transcranial optical monitoring of cerebral blood flow and hemoglobin concentration in acute stroke patients during positional interventions," Annals of Neurology, Optics Express 17(5):3884-3902 (2009)
  13. M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh. “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial doppler ultrasound,” Optics Express, 17(15):12571-12581 (2009)
  14. A. G. Yodh and J. H. Greenberg, "Acute functional recovery of cerebral blood flow after forebrain ischemia in rat," J Cereb Blood Flow Metab 28(7), 1275-1284 (2008)
  15. G. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. A. Detre, A. G. Yodh, “Diffuse Correlation Spectroscopy for Muscle Blood Flow: Validation with Arterial-Spin-Labeling Perfusion MRI,” Optics Express, 15:1064-1075, 2007
  16. U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee and A. G. Yodh, "Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies," Optics Express 15(23), 15507-15516 (2007)
  17. A. Cerussi, B. J. Tromberg and A. G. Yodh, "Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy," J Biomed Opt 12(5), 051903 (2007)
  18.  C. Zhou, G. Yu, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh and T. Durduran, "Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain," Optics Express 24(3), 1125-1144 (2006)
  19. G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn and A. G. Yodh, "Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light," Photochem Photobiol 82(5), 1279-1284 (2006)
  20. U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance and A. G. Yodh, "Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study," J Biomed Opt 11(6), 064021 (2006)
  21. K. L. Du, R. Mick, T. M. Busch, T. C. Zhu, J. C. Finlay, G. Yu, A. G. Yodh, S. B. Malkowicz,
  22. D. Smith, R. Whittington, D. Stripp and S. M. Hahn, "Preliminary results of interstitial motexafin lutetium-mediated PDT for prostate cancer," Lasers Surg Med 38(5), 427-434 (2006)
  23. G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, H. M. Saunders, C. M. Sehgal, E. Glatstein, A. G. Yodh and T. M. Busch, "Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy," Clin Cancer Res 11(9), 3543-3552 (2005)
  24. G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, 3rd and A. G. Yodh, "Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies," J Biomed Opt 10(2), 024027 (2005)
  25. T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki and A. G. Yodh, "Diffuse optical measurement of blood flow in breast tumors," Opt Lett 30(21), 2915-2917 (2005)
  26. T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou and A. G. Yodh, "Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation," Opt Lett 29(15), 1766-1768 (2004)
  27. T. Durduran, M. G. Burnett, G. Yu, C. Zhou, D. Furuya, A. G. Yodh, J. A. Detre and J. H. Greenberg, "Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry," J Cereb Blood Flow Metab 24(5), 518-525 (2004)