Dr. Ashish Kala

Sun Pharma Advanced Research Company (SPARC)

Email: ashishkumarkala@gmail.com

Qualifications

2015: Interdisciplinary Ph.D. in Pharmaceutical Sciences & Chemistry,

University of Missouri-Kansas City (UMKC), USA

2005: Bachelors of Pharmacy, Devi Ahilya Vishwavidyalaya, Indore, India

Publications (Selected)

1. Kala, A., Patel Y. T., Davis A., Stewart C. F. “Development and validation of LC-MS/MS methods for the measurement of ribociclib, a CDK4/6 inhibitor, in mouse plasma and Ringer’s solution and its application to a cerebral microdialysis study”, Journal of Chromatography B, 2017, 1057,110-117.
2. Patel, Y.; Davis, A.; Kala, A.; Roberts, J.; Jacus, M.; Baker, S; Roussel, M.F; Stewart, C.F. “CNS penetration of the CDK 4/6 inhibitor ribociclib (LEE011) in non-tumor bearing mice and mice bearing orthotopic brain tumors”, Neuro-Oncology, 2016, 18 (6), 152
3. Kala, A.; Jain, P.K.; Friedman, S.H. “Patterning of cells through patterning of biology”, Molecular Biosystems, 2014, 10, 1689-1692.
4. Kala, A.; Jain, P.K.;Karunakaran, D.; Shah, S.; Friedman, S.H. “The synthesis of tetra-modified RNA for the multi-dimensional control of gene expression using Light Activated RNA Interference (LARI)”, Nature Protocols,2014, 9(1), 11-20.
5. Kala, A.; Friedman, S.H. “Enhanced light-activated RNA interference using phosphorothioate-based dsRNA precursor of siRNA”, Pharmaceutical Research, 2011, 28 (12), 3050-3057.
6. Shah, S.; Jain, P.K.; Karunakaran, D.; Kala, A.; Rangarajan, S.; Friedman, S.H. “Light Activated RNA Interference Using Photo-cleavable siRNA”,  JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2009, 26 (6), 810-810.
7. Shah, S.; Jain, P.K.; Kala, A.; Karunakaran, D.; Friedman, S.H. “Light activated RNA interference using double stranded siRNA precursors modified using a remarkable regiospecificity of diazo-based photo labile groups”, Nucleic Acids Research, 2009, 37(13), 4508-4517.

Personal Website:

https://scholar.google.com/citations?user=ITeIlEoAAAAJ