Prof. Hülya Cicek

Medical Biochemistry Department

School of Medicine Gaziantep University, Turkey



2019 Prof.Dr., Biochemistry and Clinical Biochemistry Department, University of Gaziantep in Gaziantep, Turkey

2013 Assoc.Prof., Biochemistry and Clinical Biochemistry Department, University of Gaziantep in Gaziantep, Turkey

2007 Asst.Prof., Biochemistry and Clinical Biochemistry Department, University of Gaziantep in Gaziantep, Turkey

2004 Ph.D., Biochemistry and Clinical Biochemistry Department, University of Gaziantep in Gaziantep, Turkey

1991 M.D., University of Cukurova in Adana, Turkey

Publications (Selected)

  1. Gürbüz H, Zengin Y, Gündüz E, Durgun HM, Dursun R, İcer M, Üstündağ M, Orak M, Güloğlu C, Cicek H. Evaluation of blood and blood products transfusions in Dicle University Faculty of Medicine Research Hospital Emergency Department. Euroasia Journal of Mathematics, Engineering, Natural & Medical Science. 2021 July; 8(16): 36-48.
  2. Yılmaz N, Yıldırım M, Savaş HS, Cicek H, Sever ÖN. The role of HMGB1 in gastrointestinal cancers. Archives of Medical Science - Civilization Diseases. 2021;6(1):1-7. doi:10.5114/amscd.2021.105385.
  3. Kilic B, Cicek H, Mete AÖ, Ganidagli S, Ugur BK. Effects of Parenteral Glutamine Supplementation on Endocan Levels in Septic Patients. Eastern Journal of Medicine, 2021; 26(1): 157-164
  4. Cicek H, Alkarkhi LA, Gürbüz H, Erbağcı Z. Serum Cytokine Profiles in Patients with Psoriasis. Acta Scientific Medical Sciences 2021 May; 5(5):13-22.
  5. Kaya Uğur B, Cicek H, Kul S, Mete Ö, Yılmaz M. Effect of a novel extracorporeal cytokine apheresis method on endocan, copeptin And interleukin-6 levels in sepsis: An observational prospective study. Transfus Apher Sci. 2020 Dec; 59(6):102919. doi: 10.1016/j.transci.2020.102919. Epub 2020 Aug 25. PMID: 32912735.
  6. Benlier N, Solakhan M, Yıldırım Z, Kaya V, Yıldırım ÖA, Orhan N, Cicek H, Yıldırım M. A novel diagnostic tool for the detection of bladder cancer: Measurement of urinary high mobility group box-1. Urol Oncol. 2020 Aug; 38(8):685.e11-685.e16. doi: 10.1016/j.urolonc.2020.03.025. Epub 2020 Apr 17. PMID: 32312640.
  7. Mendeş B, Karakuzulu M, Cicek H, Elboğa U, Mendeş M. The Relationship Between Muscle Strength and Bone Mineral Density in Footballers. Turkiye Klinikleri J Sports Sci. 2020; 12(2):120-8.
  8. Solakhan M, Cicek H, Benlier N, Yıldırım Z, Sever ÖN, Orhan N, Yıldırım M. Role of HMGB1 in Prostate Cancer. European Journal of Therapeutics. doi: 10.5152/Eur J Ther. 2019. 19052
  9. Benlier N, Yener BN, Cicek H. The Effects of Fasudil on Inflammation Induced by Amyloıd Beta Peptide in an Astrocyte Cell Line. Neurol Res Surg. 2019 Nov; 2(2): 1-6.
  10. Cicek H, Saygılı Ö, Sever ÖN Kaya V, Ulusal H, Yıldırım M. The Diagnostic Role of A-kinase Anchoring Protein 12, Bcl-2 and High Mobility Group Box Protein-1 Levels in Breast Cancer. Journal of Oncological Sciences. doi: 10.1016/j.jons. 2019. 09.003
  11. Cicek H, Ciftci Aksoy Ü G, Kul S. Consistency of High Performance Liquid Chromatography, Electrochemiluminescence and Mass Spectrometry Methods for Vitamin D Measurement. Acta Scientific Medical Sciences. 2019 Aug; 3 (8): 15-22.
  12. Sever ÖN, Cicek H, Benlier N, Yıldırım Z, Yıldırım ÖA, Erdogan MB, Yıldırım M. Prognostic role of serum HMGB1, endocan, and caveolin level in non-small cell lung cancer. J Mol Cancer. 2019 Apr; 2(2):12-14.
  13. Yener BN, Benlier N, Cicek H. Assessment of cell viability in an astrocyte cell line exposed to amyloid beta peptide and Fasudil. J Pharmacol Res 2019;3(1):1-4. Index
  14. Benlier N, Erdoğan MB, Keceoğlu S, Orhan N, Cicek H. Association of high mobility group box 1 protein with coronary artery disease. Asian Cardiovasc Thorac Ann. 2019 May; 27(4):251-55.
  15. Solakhan M, Cicek H, Orhan N, Yıldırım M. Role of Native Thiol, Total Thiol and Dynamic Disulphide in Diagnosis of Patient with Prostate Cancer and Prostatitis. Int Braz J Urol. 2019 Jan 5; 45. doi: 10.1590/S1677-5538.
  16. Tekayev M, Bostancieri N, Saadat KASM, Turker M, Yuncu M, Ulusal H, Cicek H, Arman K. Effects of Moringa oleifera Lam Extract (MOLE) in the heat shock protein 70 expression and germ cell apoptosis on experimentally induced cryptorchid testes of rats. Gene. 2019 Mar 10; 688:140-150. doi: 10.1016/j.gene.2018.11.091.
  17. Deveci HA, Nur G, Cicek H, Karapehlivan M. Evaluation of oxidative stress factors in patients with osteoporosis. Medicine Science International Medical Journal 2017 Sept; 6(3):479-82.
  18. Cicek H, Guleken N, Öztuzcu S, Sevinc A. Vitamin D receptor polymorphisms and related biochemical parameters in various cancer species. Turk J Biochem 2017 April; 42(2):161-68.
  19. Cocelli LP, Cicek H, Isik M, Zer Y. The Effect of Tramadol and Tramadol with Gabapentin Combination in Patients with Lumbar Disc Herniation after Epidural Steroid Injection. Turkish Journal of Medical Sciences. 2015 Oct;45(6):1214-9.
  20. Madenci E, Gücbey Ş, Koca İ, İbas E, Cicek H. Serum Total Oxidative and Antioxidative Status in Patients with Postmenopausal Osteoporosis. Nobel Med 2015; 11(1): 83-86.
  21. Demirpence Ö, Yıldırım M, Avcı A, Kılıc E, Bilgetekin H, Deniz HG, Kaya V, Cicek H. The Role of Trace Elements in the Malignant-Benign Differentation of Pleural Effusions. Journal of Clinical and Analytical Medicine 2015 Apr; 286(1):1-4.
  22. Cocelli LP, Dikensoy E, Cicek H, Ibar Y, Kul S, Balat O. Pseudocholinesterase in gestational diabetes: positive correlation with LDL and negative correlation with triglyceride. Arch Gynecol Obstet. 2012 Jul; 286(1):43-9.
  23. Kadi C, Cicek H. The evaluation of myomectomies performed during cesarean section in our clinic. Niger Med J. 2011 Jul; 52(3):186-8.
  24. Acilmis YG, Dikensoy E, Kutlar AI, Balat O, Cebesoy FB, Ozturk E, Cicek H, Pence S. Homocysteine, Folic Acid and Vitamin B12 Levels in Maternal and Umbilical Cord Plasma and Homocysteine Levels in Placenta in Pregnant Women with Pre-eclampsia. J Obstet Gynaecol Res. 2011 Jan; 37(1):45-50.
  25. Dikensoy E, Balat O, Cebesoy B, Ozkur A, Cicek H, Can G. The effect of Ramadan fasting on maternal serum lipids, cortisol levels and fetal development. Arch Gynaecol Obstet 2009 May; 279:119-123.
  26. Ozer O, Davutoglu V, Ercan S, Akcay M, Sari I, Sucu M, Celik A, Aksoy N, Cicek H, Al B. Plasma Urotensin II as a Marker for Severity of Rheumatic Valve Disease. Tohoku J Exp Med. 2009 May; 218(1):57-62.
  27. Zer Y, Karaoglan I, Cicek H, Karagoz ID, Saglam M. Evaluation of the Patients with Low Levels of Anti-Hcv Positivity. Mikrobiyol Bul. 2009 Jan; 43(1):133-9.
  28. Bayil S, Cicek H, Cimenci IG, Hazar M. How Volatile Organic Compounds Affect Free Radical and Antioxidant Enzyme Activity in Textile Workers. Arh Hig Rada Toksikol. 2008 Dec; 59(4):283-7.
  29. Dikensoy E, Balat O, Cebesoy B, Ozkur A, Cicek H, Can G. Effect of Fasting During Ramadan on Fetal Development and maternal health. J Obstet Gynaecol Res. 2008 Aug; 34(4):494-498.
  30. Dikensoy E, Balat O, Pence S, Akcali C, Cicek H. The Risk of Hepatotoxicity During Long-Term and Low-Dose Dose Flutamide Treatment in Hirsutism. Arch Gynaecol Obstet 2008 Jul; 8.
  31. Geyikli I, Bayıl S, Cicek H, Erbağcı Z. Plasma Adenosine Deaminase Activities Chronic at Urticaria Patients Online Journal of Euro Asian Dermatology, 2007; 1(1).
  32. Yilmaz N, Cicek HK, Celik A, Meram I, Kocabas R, Davutoglu V. Diagnostic Value of Homocysteine, C-Reactive Protein and Bilirubin for Coronary Artery Disease. Eastern Mediterranean Health Journal, 2007; 13(3): 522-35.
  33. Cicek H, Bayil S, Zer Y, Celik A, Geyikli I. Comparison of Lipoprotein(a) Levels between Elderly and Middle-Aged Men with Coronary Artery Disease. Ann N Y Acad Sci, Annals 2007; 1100:179-184.
  34. Bayraktaroglu Z, Yilmaz N, Cicek HK, Karafak A, Gül E. Platelet Storage Time and Cytokine (IL-2R, IL-8, TNF-Α) Levels. Eastern Mediterranean Health Journal 2007; 13(1): 79-84.
  35. Yilmaz N, Herken H, Cicek HK, Celik A, Yurekli M. Increased Levels of Nitric Oxide, Cortisol and Adrenomedullin in Male Patients with Chronic Schizophrenia. Med Princ Pract 2007; 16(2):137-41.
  36. Bayil S, Celik A, Cicek H, Geyikli İ, Tarakcioglu M. Free Radical and Antioxidant Enzyme Levels at Exposure of Volatile Organic Compounds in Workers. Saudi Med J. 2007 Feb; 28(2): 290-1.
  37. Yilmaz N, Cicek HK, Celik A, Davutoglu V. Diagnostic Value of Bilirubin Concentrations Compared to Novel and Traditional Biomarkers in Atherosclerosis with Coronary Artery Disease. Saudi Med J. 2006 Aug; 27(8): 1262-4.
  38. Yilmaz N, Kepkep N, Cicek HK, Celik A, Meram I. Relation of Parity and Homocysteine to Bone Mineral Density of Postmenopausal Women. Clin Lab 2006; 52(1-2): 49-56.
  39. Tarakcioglu M, Erbagcı AB, Cekmen M, Usalan C, Cicek H, Ozaslan J, Camci C. Acute Effect of Haemodialysis on Serum Markers of Myocardial Damage. Int J Clin Pract 2002; 56(5): 328-332.

Profile Details

I also conduct academic studies in various disciplines. I worked as a thesis supervisor at the master's graduate and doctoral levels of many students. I am a member of editorial or reviewer boards of international eminent journals. I managed the central laboratory of the training and research hospital for a long time. My research interests are focused on clinical biochemistry, biochemical technics, molecular biology, genetics, cancer research, vitamin D, cardiac biomarkers, urology, neurologic diseases, dermatological biomarkers, obstetrics and gynecology and homocysteine. I am a member of The Turkish Society of Biochemistry, The Turkish Society of Clinical Biochemistry and Society of Clinical Biochemistry Experts. My native language is Turkish and foreign language is English.

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