Dr. Deepa Jonnalagadda

Neuroscience and Aging Research Center

Drug Discovery Research Program

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA

Email: djonnalagadda@sbpdiscovery.org

Qualifications

2013 Ph.D., Molecular and Cellular Biochemistry University of Kentucky College of Medicine, Lexington, Kentucky, USA

2006 M.Sc., Biochemistry University of Hyderabad, Hyderabad, India

2004 B.Sc., Biotechnology Biochemistry and Chemistry Aurora Degree College, Hyderabad, India

Publications (Selected)

1. Jonnalagadda D , Izu L, and Whiteheart SW. (2012) Platelet secretion is kinetically heterogeneous in agonist-responsive manner (Blood 2012)
2. Jonnalagadda D , Sunkara M, Morris AJ, and Whiteheart SW. (2014) Granule-mediated release of sphingosine-1-phosphate from activated platelets (BBA Lipids 2014)
3. Groves A* Kihara Y*, Jonnalagadda D * , Rivera R, Kennedy G, Mayford M, and Chun J. (2018) A functionally defined in vivo astrocyte population identified by c-Fos activation in a mouse model of multiple sclerosismodulated by S1P signaling: immediate-early astrocytes ( ieAstrocytes )" (eNeuro 2018)
4. Chun J, Kihara Y, Jonnalagadda D , and Blaho V. (2019) Fingolimod: Lessons learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders (Annual Reviews 2019)
5. Jonnalagadda D , Kihara Y, Groves A, Rivera R, Kennedy G, Quadros EV, Mayford M, and Chun J. Sphingosine phosphate signaling effects in immediate-early astrocytes (ieAstrocytes) 2019 Keystone Symposia Conference Z1: Neural Environment in Disease: Glial Responses and Neuroinflammation
6. Jonnalagadda D , Groves A, Kihara Y, Mayford M and Chun J. Fingolimod Mediates Vitamin B12 Regulation through Astrocytic Sphingosine 1-Phosphate Signaling. 2018 ACTRIMS forum , San Diego, CA.
7. Jonnalagadda D , Groves A, Kihara Y, Mayford M and Chun J. Astrocytic activity modulated by S1P signaling in experimental autoimmune encephalomyelitis revealed in a c-Fos reporter mouse. 2016 Neuroscience , San Diego, CA.
8. Jonnalagadda D , Groves A, Kihara Y, Mayford M and Chun J. c-Fos reporter reveals astrocytic activity modulated by S1P signaling in experimental autoimmune encephalomyelitis. 2016 7 th International conference on Phospholipase A2 and lipid mediators , La Jolla, CA.
9. Jonnalagadda D , Sunkara M, Morris AJ, and Whiteheart SW. Platelets release Sphingosine 1-Phosphate by regulated exocytosis. 2013 South – East Regional Lipid Conference , Cashiers, NC.
10. Jonnalagadda D , Sunkara M, Morris AJ, and Whiteheart SW. Platelets release Sphingosine 1-Phosphate by regulated exocytosis. 2013 Gill Heart Cardiovascular Research Day , Lexington, KY.
11. Jonnalagadda D , Sunkara M, Morris AJ, and Whiteheart SW. Platelet Secretion – Release of Sphingosine-1-Phosphate. 2012 Mid-West Platelet Conference , Case Western Reserve University, Cleveland, Ohio.
12. Jonnalagadda D , Sunkara M, Morris AJ, and Whiteheart SW. Mechanism of S1P Release from Platelets . 2012Vasculata (North American Vascular Biology Organization, NAVBO) , Nashville, TN.
13. Jonnalagadda D , Izu L, and Whiteheart SW. Heterogeneity in Platelet Secretion. 2010 Mid-West PlateletConference at Chapel Hill, UNC.
14. Jonnalagadda D , Izu L, and Whiteheart SW. Heterogeneity in Platelet Secretion. 2009 ASBMB (National Meeting of American Society of Biochemistry and Molecular Biology) , New Orleans, LA.
15. Jonnalagadda D and Mitra CK. Covalent coupling of glucose oxidase on gold nanoparticles. 2006 Internationalsymposium “Nano-Bio Interface” . University of Kolkata, Kolkata, India.