Dr. Farrukh Aqil

University of Louisville, USA

Assistant Professor

Email: farrukh.aqil@louisville.edu

Qualifications

2006 Ph.D., Aligarh Muslim University, India

2000 M.Sc., Aligarh Muslim University, India

1998 B.Sc., Aligarh Muslim University, India

Publications (Selected)

1. Aqil F, Munagala R, Jeyabalan J, Agrawal AK, Gupta R. Exosomes for the enhanced bioavailability and efficacy of curcumin. AAPS [American Assn of Pharmaceutical Sciences] Journal 2017 Nov;19(6):1691-702. PMID: 29047044.
2. Aqil F, Jeyabalan J, Agrawal AK, Kyakulaga AH, Parker L, Munagala R, Gupta RC. Exosomal delivery of berry anthocyanidins for the management of ovarian cancer. Food & Function 2017 Nov 15;15;8(11):4100-7. PMID: 28991298.
3. Aqil F, Jeyabalan J, Munagala R, Ravoori S, Vadhanam MV, Schultz DJ, Gupta R. Chemoprevention of rat mammary carcinogenesis by Apiaceae spices. International Journal of Molecular Science 2017 Feb 16;18(2):E425. PMID: 28212313. PMCID: PMC5343959.
4. *Sherwood LC, *Aqil F, *Vadhanam MV, Jeyabalan J, Hoetkar D, Srivastava S, O’Toole M, Cambron S, Spencer W, Parker L, Gupta RC. Development of a goat model for evaluation of withaferin A: Cervical implants for the treatment of cervical intraepithelial neoplasia. Experimental & Molecular Pathology 2017 Dec;103(3):320-9. (* equal contribution). PMID: 29157955.
5. *Agrawal AK, *Aqil F, Jeyabalan J, Spencer WA, Beck J, Gachuki BW, Alhakeem SS, Oben K, Munagala R, Bondada S, Gupta R. Milk-derived exosomes for oral delivery of paclitaxel. Nanomedicine 2017 Jul;13(5):1627-36. (*equal contribution). PMID: 28300659.
6. Munagala R, Aqil F, Jeyabalan J, Agrawal AK, Mudd AM, Al-Hassan K, Vadhanam MV, Gupta R. Exosomal formulation of anthocyanidins against multiple cancer types. Cancer Letters 2017 May 1;393:94-102. PMID: 28202315. PMCID: PMC5837866.
7. Husain FM, Ahmad I, Al-Thubiani AS, Abulreesh HH, AlHazza IM, Aqil F. Leaf extracts of Mangifera indicaL. inhibits quorum sensing-regulated production of virulence factors and biofilm in test bacteria. Frontiers in Microbiology 2017 Apr 24;24;8:727. eCollection 2017. PMID: 28484444. PMCID: PMC5402315.
8. Aqil F, Gupta RC. Controlled delivery of chemopreventive agents by polymeric implants. Methods in Molecular Biology 2016;1379:1-11. PMID: 2660285.
9. *Munagala R, *Aqil F, *Jeyabalan J, Gupta RC. Bovine milk-derived exosomes for drug delivery. Cancer Letters 2016 Feb 1;371(1):48-61. (* equal contribution). PMID: 26604130. PMCID: PMC4706402.
10. Munagala R, Aqil F, Gupta RC. Exosomal miRNAs as biomarkers of recurrent lung cancer. Tumor Biology 2016 Aug;37(8):10703-14. PMID: 26867772.
11. Zahin M, Ahmad I, Shireen I, Husain FM, Aqil, F. Broad spectrum antioxidant properties of 20 Indian medicinal plants. Journal of Herbs Spices and Medicinal Plants 2016;22:118-29. [ https://doi.org/10.1080/10496475.2015.1057888 ]
12. Aqil F, Jeyabalan J, Kausar H, Munagala R, Gupta RC. Lung cancer inhibitory activity of dietary berries and berry polyphenols. Journal of Berry Research 2016;6(2):105-14.
13. Aqil F, Jeyabalan J, Munagala R, Singh IP, Gupta RC. Prevention of hormonal breast cancer by dietary jamun. Molecular Nutrition and Food Research 2016 Jun;60(6):1470-81. PMID: 27030099. PMCID: PMC4927075.
14. Zahin M, Ahmad I, Aqil F. Antioxidant and antimutagenic potential of Psidium guajava. Drug & Chemical Toxicology 2017 Apr;40(2):146-53. PMID: 27268266.
15. Aqil F, Kausar H, Agrawal AK, Jeyaprakash J, Munagala R, Gupta RC. Exosomal formulation enhances therapeutic response of celastrol against lung cancer. Experimental & Molecular Pathology 2016 Aug;101(1):12-21. PMID: 27235383.
16. Cao P, Aqil F, Ravoori S, Gupta RC, Vadhanam MV. Polymeric implants for systemic delivery of green tea polyphenols. Journal of Pharmaceutical Science 2014 Mar;103(3):945-51. PMID: 24464784. PMCID: PMC4009679.
17. Zahin M, Ahmad I, Gupta R, Aqil F. Punicalagin and ellagic acid demonstrates antimutagenic activity and inhibition of benzo[a]pyrene induced DNA adducts. Biomedical Research International 2014;2014:467465. PMID: 24949451. PMCID: PMC4052943.
18. Aqil F, Shen H, Jeyabalan J, Xing X, Lehmler H, Gabriele L, Robertson LW, Gupta RC. Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants. Toxicology Report 2014 Jan 1;1:820-33. PMID: 25530946. PMCID: PMC4266188.
19. Munagala R, Aqil F, Jeyabalan J, Vadhanam MV, Gupta RC. Tanshinone IIA inhibits viral oncogene expression leading to apoptosis and inhibition of cervical cancer. Cancer Letters 2015 Jan;356(2 Pt B):536-46. PMID: 25304375.
20. Jeyabalan J, Aqil F. Soper L, Schultz D, Gupta, RC. Potent chemopreventive/antioxidant activity detected in common spices of the Apiaceae family invitro. Nutrition & Cancer 2015;67(7):1201-7. PMID: 26381237. PMCID: PMC4684170.