Dr. Ranran Wu

Perelman School of Medicine, University of Pennsylvania

Postdoctoral Scientist

Email: ranranwu@mail.med.upenn.edu

Qualifications

2016 Ph.D., Wayne State University, USA

2008 B.S., Jiangnan University, China

Publications (Selected)

1. Wu RR, Hamlow LA, He CC, Nei Y-w, Berden G, Oomens J, Rodgers MT: N3 and O2 Protonated Conformers of the Cytosine Mononucleotides Coexist in the Gas Phase. J. Am. Soc. Mass Spectrom. 2017, Accepted.
2. Wu RR, Rodgers MT: Tautomerization Lowers the Activation Barriers for N-Glycosidic Bond Cleavage of Protonated Uridine and 2'-Deoxyuridine. Phys. Chem. Chem. Phys. 2016, 18, 24451-24459.
3. Boles GC, Wu RR, Rodgers MT, Armentrout, PB: Thermodynamics and Mechanisms of Protonated Asparaginyl-Glycine Decomposition. J. Phys. Chem. B 2016, 120, 6525-6545.
4. Wu RR, Rodgers MT: Mechanisms and Energetics for N-Glycosidic Bond Cleavage of Protonated Adenine Nucleosides: N3 Protonation Induces Base Flipping and Enhances N-Glycosidic Bond Stability. Phys. Chem. Chem. Phys. 2016, 18, 16021-16032.
5. Wu RR, He CC, Hamlow LA, Nei Y-w, Berden G, Oomens J, Rodgers MT: Protonation Induces Base Rotation of Purine Nucleotides pdGuo and pGuo. Phys. Chem. Chem. Phys. 2016, 18, 15081-15090.
6. Wu RR, Rodgers MT: O2 Protonation Controls Threshold Behavior for N-Glycosidic Bond Cleavage of Protonated Cytosine Nucleosides. J. Phys. Chem. B 2016, 120, 4803-4811
7. Wu RR, He CC, Hamlow LA, Nei Y-w, Berden G, Oomens J, Rodgers MT: N3 Protonation Induces Base Rotation of 2'-Deoxyadenosine-5'-Monophosphate and Adenine-5'-Monophosphate. J. Phys. Chem. B 2016, 120, 4616-4624.
8. Wu RR, Chen Y, Rodgers MT: Mechanisms and Energetics for N-Glycosidic Bond Cleavage of Protonated 2'-Deoxyguanosine and Guanosine. Phys. Chem. Chem. Phys. 2016, 18, 2968-2980.
9. Wu RR, Yang B, Frieler CE, Berden G, Oomens J, Rodgers MT: 2,4-Dihydroxy and O2 Protonated Tautomers of dThd and Thd Coexist in the Gas Phase: Methylation Alters Protonation Preferences vs dUrd and Urd. J. Am. Soc. Mass Spectrom. 2016, 27, 410-412.
10. Yang B, Wu RR, Rodgers MT: Base-Pairing Energies of Proton-Bound Dimers and Proton Affinities of 1-Methyl-5-Halocytosines: Implications for the Effects of Halogenation on the Stability of the DNA i-motif. J. Am. Soc. Mass Spectrom. 2015, 26, 1469-1482.
11. Wu RR, Yang B, Frieler CE, Berden G, Oomens J, Rodgers MT: Diverse Mixtures of 2,4-Dihydroxy Tautomers and O4 Protonated Conformers of Uridine and 2'-Deoxyuridine Coexist in the Gas Phase. Phys. Chem. Chem. Phys. 2015, 17, 25978-25988.
12. Wang R, Yang B, Wu RR, Rodgers MT: Guided Ion Beam and Computational Studies of the Decomposition of a Model Thiourea Protein Cross-Linker. J. Phys. Chem. B 2015, 119, 3727-3742.
13. Wu RR, Yang B, Frieler CE, Berden G, Oomens J, Rodgers MT: N3 and O2 Protonated Tautomeric Conformations of 2'-Deoxycytidine and Cytidine Coexist in the Gas Phase. J. Phys. Chem. B 2015, 119, 2795-2805.
14. Kaczan CM, Rathur AI, Wu RR, Chen Y, Austin, CA, Berden G, Oomens J, Rodgers MT: Infrared Multiple Photon Dissociation Action Spectroscopy of Sodium Cationized Halouracils: Effects of Sodium Cationization and Halogenation on Gas-Phase Conformation. Int. J. Mass Spectrom. 2015, 378, 76-85.
15. Wu RR, Yang B, Berden G, Oomens J, Rodgers MT: Gas-Phase Conformations and Energetics of Protonated 2'-Deoxyadenosine and Adenosine: IRMPD Action Spectroscopy and Theoretical Studies. J. Phys. Chem. B 2015, 119, 2795-2805.
16. Wu RR, Yang B, Berden G, Oomens J, Rodgers MT: Gas-Phase Conformations and Energetics of Protonated 2'-Deoxyguanosine and Guanosine: IRMPD Action Spectroscopy and Theoretical Studies. J. Phys. Chem. B 2014, 118, 14774-14784.
17. Yang B, Wu RR, Rodgers MT: Hydrogen Bond Stabilization Energies of Proton-Bound Homodimers Determined by Guided Ion Beam Tandem Mass Spectrometry: Application to Cytosine and 5-substituted Cytosines. Anal. Chem. 2013, 85, 11000-11006.
18. Yang B, Wu RR, Rodgers MT: Infrared Multiple Photon Dissociation Action Spectroscopy of Proton-Bound Dimers of Cytosine and Modified Cytosines: Effects of Modifications on Gas Phase Conformations. J. Phys. Chem. B 2013, 117, 14191-14201

19. Yang B, Wu RR, Polfer NC, Berden G, Oomens J, Rodgers MT: IRMPD Action Spectroscopy of Alkai Metal Cation-Cytosine Complexes: Effects of Alkali Metal Cation Size on Gas Phase Conformation. J. Am. Soc. Mass Spectrom. 2013, 24, 1523-1533.

Profile Details
https://www.linkedin.com/in/ranran-wu-8564a2128/