Dr. Hani El-Nezami
University of Hong Kong, China
Email: elnezami@hku.hk
Qualifications
1999 Doctor of Philosophy (Ph.D.), Nutritional Toxicology, RMIT-University, Melbourne, Australia
1995 Master of Applied Science, Nutritional Toxicology, RMIT-University, Melbourne, Australia
1985 Bachelor of Science, Biochemistry, University of Alexandria, Alexandria, Egypt
Publications (Selected)
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El-Nezami, H. S., Nicoletti, G., Neal, G. E., Donohue, D. and Ahokas, J. T., 1995. Aflatoxin M1 in human breast milk samples from Victoria, Australia and Thailand. Food. Chem. Toxicol., 33, 173-179. (2.321, 35/75)
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El-Nezami, H. S., S. Salminen and J.T. Ahokas. 1996. Biologic control of food carcinogen using Lactobacillus GG.Nutr Today. 31, 41-43.
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El-Nezami H. S., P.E. Kankaanpää, S. Salminen and J.T. Ahokas. 1998 (a). Ability of dairy strains of lactic acidbacteria to bind food carcinogens. Food Chem. Toxicol., 36, 321-326. (2.321, 35/75)
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El-Nezami H. S., P.E. Kankaanpää, S. Salminen and J.T. Ahokas. 1998 (b). Physico-chemical alterations enhance the ability of dairy strains of lactic acid bacteria to remove aflatoxins from contaminated media. J. Food Prot., 61,466-468. (1.763, 27/107)
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Kiriavainen, P., H. ElNezami, J. Ahokas, S. Salminen and P. Wright. 1999. The effect of orally administered viable Lactobacillus GG and Propionibacterium JS on mouse lymphocyte proliferation. Clin. Diag. Lab. Immunol., 6, 799-802. (2.237, 43/91)
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Kiriavainen, P., H. El-Nezami, J. Ahokas, S. Salminen and P. Wright. 1999. The Effect of Orally Administered Viable Probiotic and Dairy Lactobacilli on Mouse Lymphocyte Proliferation. FEMS Immunol.Med. Microbiol., 26, 131-135. (1.972, 58/91)
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El-Nezami, H. S., H. Mykkänen, P., Kankaanpää, S. Salminen and J. T., Ahokas. 2000. Ability of Lactobacillus and Propionibacterium strains to remove aflatoxin B, from the chicken duodenum. 2000. J. Food. Prot., 63: 549-552. (1.763, 27/107)
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El-Nezami, H. S., H. Mykkänen, P., Kankaanpää, T., Suomalainen, J T., Ahokas and S. Salminen. 2000. The ability of a mixture of Lactobacillus and Propionibacterium to influence the faecal recovery of aflatoxins in healthy Egyptian volunteers: A pilot clinical study. Biosci. Microflora, 19: 41-45.
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Kankaanpaa, P., E. Tuomola, H. El-Nezami, J. Ahokas, and S. Salminen. 2000. Binding of aflatoxin B1 alters the adhesion properties of Lactobacillus rhamnosus strain GG in a Caco-2 model. J Food Prot., 63: 412-414. (1.763, 27/107)
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Pieridis, M, H. El-Nezami, K. Peltonen, S. Salminen and J. Ahokas. 2000. Ability of dairy strains of lactic acid bacteria to bind aflatoxin M1 in a food model. J Food Prot., 63, 645-650. (1.763, 27/107)
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Peltonen, K., H. El-Nezami, S. Salminen and J. Ahokas. 2000. Binding of aflatoxin B1 by probiotic bacteria. J. Sci. Food Agr., 80, 1942-1945. (1.333, 6/35)
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Haskard C., H. El-Nezami, P. Kankaanpää, S. Salminen, and J. T. Ahokas. 2001. Surface binding of aflatoxin B1 by lactic acid bacteria. Appl. Environ. Microbiol., 67:3086-3091. (3.801, 21/91)
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Peltonen K, H. El-Nezami, C. Haskard, J. Ahokas, and S. Salminen. 2001. Aflatoxin B1 binding by dairy strains of lactic acid bacteria and bifidobacteria. J. Dairy Sci., 84:2152-6. (2.486, 1/45)
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El-Nezami, H. S., Chrevatidis, A., Auriola, S., Salminen, S. and Mykkänen, H. Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium. 2002. Food Addit. Contam., 19: 680-686. (1.810, 26/107)
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El-Nezami, H. S., Polychronaki, N, Salminen, S. and Mykkänen, H. 2002. Binding rather than metabolism may explain the interaction of two food grade Lactobacillus strains with zearalenone and its derivative α-zearalenol. Appl. Environ. Microbiol., 68: 3545-3549. (3.801, 21/91)
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El-Nezami, H. S, C. Haskard, E. Salminen, H. Mykkänen, J. Ahokas, and S. Salminen. 2002. Lactic acid bacteria and bifidobacteria can reduce dietary exposure to aflatoxins. Br. J. Nut., 88: S115-S116. (2.764, 15/59)
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El-Nezami, H. S., Salminen, S. and Mykkänen, H. 2002. Probiotic bacteria-mycotoxins interactions: an approach to enhance food safety. Pol. J. Food. Nutr., Sci., 11:39-43.
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Lee, Y. K., El-Nezami, H. S., Haskard, C. A., Gratz, S., Puong, K. Y., Salminen S. and Mykkänen, H. 2003. A Kinetic approach to study mechanism of adsorption and desorption of aflatoxin B1 by viable and heat-treated bacteria. J. Food Prot., 66: 426-431. (1.763, 27/107)
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Gråsten, S., Liukkonen, K.H., Chevratidis, A., El-Nezami, H., Poutanen, K., Mykkänen, H. 2003. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans. Nutr. Res. 23: 1503-1514. (0.866, 48/59)
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El-Nezami, H. S., Polychronaki, N, Lee, Y. K., Haskard, C. A., Juvonen, R., Salminen S. and Mykkänen, H. 2004. Chemical moieties and interactions involved in the binding of zearalenone to the surface of Lactobacillus rhamnosus strain GG. J Agr. Food Chem. 52:4577-4581. (2.562, 2/35)
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Gratz, S., Mykkänen, H., Ouwehand, A. C., R. Juvonen, S. Salminen and El-Nezami, H. 2004. Intestinal mucus alters the ability of probiotic bacteria to bind aflatoxin B1. Appl. Environ. Microbiol., 70:6306-6308. (3.801, 21/91)
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Mykkänen H, Zhu H, Salminen E, Juvonen RO, Ling W, Jing M, Polychronaki N, Hynninen H, Mykkänen O, Salminen S, El-Nezami H. 2005. Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1, AFB-N7-guanine) in young Chinese males. Int J Cancer .,115:879-84. (4.734, 30 /143)
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Polychronaki, N., P, C. T., Mykkanen, H., Gong, Y., Amra, H., Abdel-Wahhab, M., and El-Nezami, H. 2006. Determinants of aflatoxin M1 in breast milk in a selected group of Egyptian mothers. Food addit. contam, 23: 700-708. (1.810, 26/107)
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El-Nezami, H. S., Polychronaki, N. N., Ma, J., Zhu, H., Ling, W., Salminen, E. K., Juvonen, R. O., Salminen, S. J., Poussa, T., and Mykkanen, H. M. Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China. 2006. Am. J. Clin. Nutr, 83: 1199-1203. (6.74, 3/59)
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Gratz, S., Taubel, M., Juvonen, R. O., Viluksela, M., Turner, P. C., Mykkanen, H., and El-Nezami, H. 2006. Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B(1) in rats. Appl. Environ. Microbiol., 72: 7398-7400. (3.801, 21/91)
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Polychronaki, N., West, R.M., Turner, P.C., Amra, H., Abdel-Wahhab, M., Mykkanen, H. and El-Nezami, H. (2007) A longitudinal assessment of aflatoxin M1 excretion in breast milk of selected Egyptian mothers. Food Chem Toxicol, 45, 1210-5. (2.321, 35/75)
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Gratz, S., Wu, Q.K., El-Nezami, H., Juvonen, R.O., Mykkanen, H. and Turner, P.C. (2007) Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport, metabolism, and toxicity in Caco-2 Cells. Appl Environ Microbiol, 73, 3958-64. (3.801, 21/91)
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Gråsten, S. M., Juntunen, K. S., Mättö, J., Mykkänen, O. T., El-Nezami, H., Adlercreutz, H., Poutanen, K. S., Mykkänen, H. M. (2007) High-fiber rye bread improves bowel function in postmenopausal women but does not cause other putatively positive changes in the metabolic activity of intestinal microbiota. Nutrition Res, 27, 454-61. (0.866, 48/59)
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Anwar, W.A., Khaled, H.M., Amra, H.A., El-Nezami, H. and Loffredo, C.A. (2008) Changing pattern of hepatocellular carcinoma (HCC) and its risk factors in Egypt: possibilities for prevention. Mutat Res, 659, 176-84. (5.192, 3/75)
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Halttunen, T., Collado, M.C., El-Nezami, H., Meriluoto, J. and Salminen, S. (2008) Combining strains of lactic acid bacteria may reduce their toxin and heavy metal removal efficiency from aqueous solution. Lett Appl Microbiol, 46, 160-5. (1.679, 62/91)
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Liu, C., Sun, M., Yan, X., Han, L., Zhang, Y., El-Nezami, H. and Liu, P. (2008) Inhibition of hepatic stellate cell activation following Yinchenhao decoction administration to dimethylnitrosamine-treated rats. Hepatol Res, 38, 919-29. (1.562, 40/55)
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Polychronaki, N., Wild, C.P., Mykkanen, H., Amra, H., Abdel-Wahhab, M., Sylla, A., Diallo, M., El-Nezami, H. and Turner, P.C. (2008) Urinary biomarkers of aflatoxin exposure in young children from Egypt and Guinea. Food Chem Toxicol, 46, 519-26. (2.321, 35/75)
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Turner, P.C., Wu, Q.K., Piekkola, S., Gratz, S., Mykkanen, H. and El-Nezami, H. (2008) Lactobacillus rhamnosus strain GG restores alkaline phosphatase activity in differentiating Caco-2 cells dosed with the potent mycotoxin deoxynivalenol. Food Chem Toxicol, 46, 2118-23. (2.321, 35/75)
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Hatakka, K., Holma, R., El-Nezami, H., Suomalainen, T., Kuisma, M., Saxelin, M., Poussa, T., Mykkanen, H. and Korpela, R. (2008) The influence of Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp. shermanii JS on potentially carcinogenic bacterial activity in human colon. Int J Food Microbiol, 128, 406-410. (3.486, 34/91)
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Partanen, H.A., El-Nezami, H.S., Leppanen, J.M., Myllynen, P.K., Woodhouse, H.J. and Vahakangas, K.H. (2010) Aflatoxin B1 transfer and metabolism in human placenta. Toxicol Sci. 113:216-25.
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Gratz, S., Mykkanen, H. and El-Nezami, H. (2010) Probiotics and gut health : A special focus on liver disease. World J Gastero. 16:403-10. (2.081, 33/55)
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Salminen, S., Nybom, S., Meriluoto, J., Collado, M., Vesterlund, S. and El-Nezami, H. (2010) Probiotic pathogen/toxin interaction - benefits to human health and nutrition?. Curr op Biotech. 21, 157-167. (7.485, 5/144)
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Uzuner H, Fan TP, Dias A, Guo DA, El-Nezami HS, Xu Q.Establishing an EU-China.
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consortium on traditional Chinese medicine research. (2010). Chin Med. 5:42-47 (1.79).
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Storvik M., Huuskonen P., Kyllonen T., Lehtonen S., El-Nezamy H.S., Auriola S. and Pasanen M. Aflatoxin B1 – A Potential Endocrine Disruptor – Up-regulates Cyp19a1 In Jeg-3 Cells, Toxicology Letters, 2011, 202, 161-167.
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Gratz S., John Wallace R. and El-Nezami H.S. Recent Perspectives On The Relations Between Fecal Mutagenicity, Genotoxicity, And Diet, Frontiers in Pharmacology, 2011, 2, 1-9.
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Wang Q.L., Wu Q., Tao Y.Y., Liu C.H. and El-Nezamy H.S. Salvianolic Acid-b Modulates The Expression Of drug-metabolizing Enzymes In Hepg2 Cells, Hepatobiliary Pancreat Dis. Int, 2011, 10.
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Peng J, Li D, Chan YK, Chen Y, Lamb JR, Tam PK, El-Nezami H: Effects of water uptake on melamine renal stone formation in mice. Nephrol Dial Transplant 2011.
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Partanen H, Vahakangas K, Woo CS, Auriola S, Veid J, Chen Y, Myllynen P, El Nezami H: Transplacental transfer of melamine. Placenta 2012, 33(1):60-66.
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Woo CS, Partanen H, Myllynen P, Vahakangas K, El-Nezami H: Fate of the teratogenic and carcinogenic ochratoxin A in human perfused placenta. Toxicol Lett 2012, 208(1):92-99.
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Piekkola, S., Turner, P. C., Abdel-Hamid, M., Ezzat, S., El-Daly, M., El-Kafrawy, S., Savchenko, E., Poussa, T., Woo, J. C., Mykkanen, H. and El-Nezami, H. (2012). Characterisation of aflatoxin and deoxynivalenol exposure among pregnant Egyptian women. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 29(6), 962-71.