Prof. Mircea Darabantu

University Babes-Bolyai, Cluj-Napoca, Romania

Email: darab@chem.ubbcluj.ro

Qualifications

2002 Present Full time Professor

1997–2002 Assist. Prof.

1990–1997 Full time Lecturer, University Babes-Bolyai Cluj-Napoca, Chemistry and Chemical Engineering

1984–1990 Scientist

1983-1984 Chemical Engineer, Chemical Pharmaceutical Research Institute Bucharest

1982–1983 Full time Chemical Engineer

Publications (Selected)

1. F. Popa, P. Lameiras, E. Henon, O. Moldovan, A. Martinez, C. Bâtiu, Y. Ramondenc and M. Darabantu*,“Amino-s-triazines. Synthesis and Stereochemistry of Restricted Rotational Phenomena (I). First Use of a C-2-Substituted Serinol in Tandem with Masked 4-Piperidone for Selective Amination of Cyanuric Chloride”. Can. J. Chem. 2011, 89(10), 1207-1221.
2. F. Popa, P. Lameiras, E. Henon, O. Moldovan, A. Martinez, C. Bâtiu, Y. Ramondenc and M. Darabantu*Can. J. Chem. 2010, accepted.
3. “Synthesis and Conformational Analysis of the First 3-Oxa-7-thia-1-r-azabicyclo[3.3.0]-c-5-octane Single Functionalised at the C-5 Position”.
4. A. But, P. Lameiras, I. Silaghi-Dumitrescu, C. Batiu, S. Guillard, Y. Ramondenc and M. Darabantu*Letters in Organic Chemistry, 2010, 7(4), 283-290.
5. “(Masked)serinols: molecules, biomolecules, building-blocks, supramolecules Part (II): serinolic approaches in current organic synthesis”M. Darabantu*Curr. Org. Synth., 2010, 7(3), 235-275.
6. “(Masked)serinols: molecules, biomolecules, building-blocks, supramolecules Part (I): syntheses based on serinols’ reactivity with carbonyl electrophiles”M. Darabantu*Curr. Org. Synth., 2010, 7(2), 120-152.
7. Serinolic Approach in the Synthesis of the 3-Oxa-7-thia-1-azabicyclo[3.3.0]octane Skeleton Functionalised at the C-5 position” A. But, C. Batiu, Y. Ramondenc and M. Darabantu*Revue Roumaine de Chimie, 2009, 54(2), 127-133.
8. “Serinolic Amino-s-triazines: Iterative Synthesis and Rotational Stereochemistry Phenomena as N-substituted Derivatives of 2-Aminopropane-1, 3-diols” M. Pintea, M. Fazekas, P. Lameiras, I. Cadis, C. Berghian, I. Silaghi-Dumitrescu, F. Popa, C. Bele, N. Plé and M. Darabantu* Tetrahedron, 2008, 64(37), 8851–8870.
9. “Serinolic Amino-s-triazines: Iterative Synthesis of N-Substituted Amino-1, 3-dioxane Derivatives from l-(p-Nitrophenyl)serinols and Rotational Stereochemistry Phenomena” M. Fazekas, M. Pintea, P. Lameiras, A. Lesur, C. Berghian, I. Silaghi-Dumitrescu, N. Plé and M.  Darabantu*Eur. J. Org. Chem., 2008, 2473-2494.
10. “Electrochemical Behavior of a New s-Triazine Based Dendrimer”V. Lates, D. Gligor, M. Darabantu and L. M. Muresan J. Appl. Electrochem., 2007, 37(5), 631-636”First Synthesis of a G-2 Melamine Dendrimer with Serinolic Peripheral Groups”.
11. M. Darabantu*, M. Pintea, M. Fazekas, P. Lameiras, C. Berghian, I. Delhom, I. Silaghi-Dumitrescu, N. Plé and A. TurckLetters in Organic Chemistry, 2006, 3(12), 905-910.
12. “α-(3,7-Dioxa-r-1-azabicyclo[3.3.0]oct-c-5-ylmethoxy)-diazines (II): Functionalisation via Directed Ortho-Metallation and Cross-Coupling Reactions”C. Berghian, E. Condamine, N. Plé, A. Turck, I. Silaghi-Dumitrescu, C. Maiereanu and M. Darabantu*Tetrahedron, 2006, 62(31), 7339-7354.
13. “α-(3,7-Dioxa-r-1-azabicyclo[3.3.0]oct-c-5-ylmethoxy)-diazines (I): Synthesis and Stereochemistry. Extension to s-Triazine Series”C. Berghian, P. Lameiras, L. Toupet, E. Condamine, N. Plé, A. Turck, C. Maiereanu and M.
14. Darabantu*Tetrahedron, 2006, 62(31), 7319-7338.
15. “First Synthesis, Rotamerism and Herbicidal Evaluation of Substituted s-Triazines with Amino-1, 3-dioxane Groups” M. Fazekas, M. Darabantu*, M. Pintea, P. Lameiras, C. Bele, C. Berghian and N. PléHeterocyclic Commun., 2006, 12(2), 151-156.
16. “First Synthesis, Rotamerism and Herbicidal Evaluation of Substituted s-Triazines with Serinolic Fragment” M. Pintea, M. Darabantu*, M. Fazekas, P. Lameiras, C. Berghian, I. Delhom, C. Bele and N.Plé Heterocyclic Commun., 2006, 12(2), 135-140.
17. “First  Example  of  Long  Distance  Stereocontrolled  Synthesis  in  1-Aza-3,7-dioxabicyclo[3.3.0.]octane Series”C. Maiereanu, M. Darabantu*, E. Condamine, G. Plé,  Y. Ramondenc, M. Fazekas, M. Pintea and C. BerghianHeterocyclic Commun., 2005, 11(3-4), 305-310.
18. “Electroreduction of (1S,2S)-2-Amino-1-(4-nitrophenyl)-propane-1,3-diol Derivatives. Behaviour of Electrogenerated Species and Application to Organic Synthesis”C. V. Cristea, C. Moinet, M. Jitaru and M. Darabantu J. Appl. Electrochem., 2005, 35(9), 845-849.
19. “Aryl-Aryl Bond Formation in Pyridine and Diazine Series. Diazines Part 41” L. Boully, M. Darabantu, A. Turck and N. Plé J. Heterocyclic Chem., 2005, 42(7), 1423-1428.
20. “Metalation of Pyridin-2-yldiazines. Use of Pyridine Ring as Ortho-Directing Group. Diazines Part 45” C. Berghian, M. Darabantu, A. Turck and N. Plé Tetrahedron, 2005.
21. Synthesis of New Polyaza Heterocycles. Diazines. Part 42” M. Darabantu, L. Boully, A. Turck and N. Plé Tetrahedron, 2005, 61(11), 2897-2905.
22. First Examples of the Conformation Chirality of Heterobicyclo[3.3.0]ctanes: 3,7-Dioxa-r-1-azabicyclo[3.3.0]oct-c-5-yl-methoxypyrazines”C. Berghian, M. Darabantu*, P. Lameiras, N. Plé and A. TurckHeterocyclic Commun., 2005, 11(6), 517-522.
23. 3,7-Dioxa-1-azabicyclo[3.3.0]octan-2-ones  Based  on l-Phenylserinols  via  the Ring-Ring or Ring-Chain  Tautomerism  of  their  Imino-Derivatives”C. Maiereanu, M. Darabantu*, G. Plé, Y. Ramondenc and L. ToupetRevue Roumaine de Chimie,2005, 50(2), 103-112.
24. “Ring-Ring Tautomerism of Some Spirooxazolidines Derived from l-Phenylserinols”.
25. C. Maiereanu, M. Darabantu*, G. Plé, Y. Ramondenc and C. BerghianRevue Roumaine de Chimie, 2005, 50(1), 29-40.
26. “Adjacent Ring Directed Ortho Metallation by the 2-Pyridyl Group in 2-Pyridyldiazines”C. Berghian, M. Darabantu*, N. Plé and A. Turck Revue Roumaine de Chimie, 2005, 50(1), 41-46.
27. “3,7-Dioxa-1-azabicyclo[3.3.0]octanes  Substituted  at  C-5  position. From Local to Global Stereochemistry”M. Darabantu*, C. Maiereanu, I. Silaghi-Dumitrescu, L. Toupet, E. Condamine, Y. Ramondenc, C. Berghian, G. Plé and N. Plé Eur. J. Org. Chem., 2004, 12, 2644-2661.
28. “Quantitative Structure – Retention Activity Relationship of Some 1,3-Oxazolidine Systems by RP-HPTLC and PCA” C. Sarbu, D. Casoni, M. Darabantu and C. MaiereanuJ. Pharm. Biomed. Anal., 2004, 35(1), 213-219.
29. “A Complex Problem of Diastereoisomerism: Synthesis and Stereochemistry of 1,4-Bis-{r-1-aza-c-5-ethyl-3,7-dioxabicyclo[3.3.0]octane-c-2-yl}-benzene C. Maiereanu, L. Toupet, E. Condamine, I. Silaghi-Dumitrescu, G. Plé, Y. Ramondenc and M. Darabantu* Revue Roumaine de Chimie, 2004, 49(7), 595-602.
30. “New 1,4-Disubstituted Phthalazines: Synthesis, Structure and Herbicidal Evaluation”C. Bele and M. Darabantu* Heterocyclic Commun., 2003, 9(6), 641-646.
31. “Relative Ortho-directing Power of Fluorine, Chlorine and Methoxy Group for the Metallation Reaction   in the Diazine Series. Diazines XXXV” F. Toudic, A. Turck, N. Plé, G. Quéguiner, M. Darabantu, T. Lequeux and J. C. Pommelet J. Heterocyclic Chem., 2003, 40(5), 855-860.