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Chapter 1 Eicosanoid and eicosanoid-related inflammatory
mediators and exercise intolerance
in heart failure with preserved ejection
fraction
Emily S. Lau 1,2,16, Athar Roshandelpoor3,16, Shahrooz Zarbafian1,4, Dongyu Wang3,5, James S.Guseh 1,2, Norrina Allen6, Vinithra Varadarajan7, Matthew Nayor8, Ravi V. Shah9, Joao A. C. Lima 7, Sanjiv J. Shah 10,11, Bing Yu 12,Mona Alotaibi13, SusanCheng 14
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14
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Chapter 2 The FADS1 genotypes modify the effect of linoleic acid‑enriched diet
on adipose tissue inflammation via pro‑inflammatory eicosanoid
metabolism
Maija Vaittinen1 · Maria A. Lankinen1 · Pirjo Käkelä2 · Jyrki Ågren3 · Craig E. Wheelock4 · Markku Laakso5,6 · Ursula Schwab1,7 · Jussi Pihlajamäki1,7
PDF (1271 KB)
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26
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Chapter 3 A genome-wide association study identifies 41 loci
associated with eicosanoid levels
Eugene P. Rhee 1✉, Aditya L. Surapaneni2,3, Pascal Schlosser 3, Mona Alotaibi4, Yueh-ning Yang5, Josef Coresh 3, Mohit Jain4, Susan Cheng 6,7, Bing Yu 5 & Morgan E. Grams
PDF (626 KB)
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35
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Chapter 4 Tissue pretreatment for LC–MS/MS analysis of PUFA and eicosanoid
distribution in mouse brain and liver
Madlen Reinicke1 & Juliane Dorow1 & Karoline Bischof1 & Judith Leyh2 & Ingo Bechmann2 & Uta Ceglarek1,3
PDF (605 KB)
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48
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Chapter 5 Eicosanoid lipidome activation
in post‑mortem brain tissues of individuals
with APOE4 and Alzheimer’s dementia
Brandon Ebright1, Isaac Assante1,2, Roy A. Poblete2, Shaowei Wang2, Marlon V. Duro2, David A. Bennett3, Zoe Arvanitakis3, Stan G. Louie1,2*† and Hussein N. Yassine2*†
PDF (5149 KB)
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61
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Chapter 6 SILAC‑based quantitative proteomics
to investigate the eicosanoid associated
inflammatory response in activated
macrophages
Nicole Brace1, Ian L. Megson1, Adriano G. Rossi2, Mary K. Doherty1† and Phillip D. Whitfield
PDF (3257 KB)
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80
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Chapter 7 Nanomolar EP4 receptor potency
and expression of eicosanoid‑related
enzymes in normal appearing colonic mucosa
from patients with colorectal neoplasia
Ulrike Ries Feddersen1*, Sebastian Kjærgaard Hendel1, Mark Alexander Berner‑Hansen1, Thomas Andrew Jepps2, Mark Berner‑Hansen1 and Niels Bindslev2
PDF (1284 KB)
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91
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Chapter 8 A single extraction 96-well method for LC-MS/MS quantification of urinary
eicosanoids, steroids and drugs
Julia Sieminska a,b, Johan Kolmert a, Javier Zurita a, Kurt Benkestock c, Johanna Revol-Cavalier a, Jacek Niklinski d, Joanna Reszec e, Sven-Erik Dahl´en f,g, Michal Ciborowski b,*, Craig E. Wheelock
PDF (2711 KB)
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104
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Chapter 9 Eicosanoids in the Pancreatic Tumor Microenvironment—A
Multicellular, Multifaceted Progression
Vikas B. Gubbala,1 Nidhi Jytosana,2 Vincent Q. Trinh,3 H. Carlo Maurer,4,5 Razia F. Naeem,1 Nikki K. Lytle,1 Zhibo Ma,1 Steven Zhao,6 Wei Lin,7 Haiyong Han,7 Yu Shi,8,† Tony Hunter,8 Pankaj K. Singh,9 Kenneth P. Olive,4 Marcus C. B. Tan,3,10,11 Susan M. Ka
PDF (5960 KB)
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120
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Chapter 10 Mild COVID-19 imprints a long-term inflammatory eicosanoidand
chemokine memory in monocyte-derived macrophages
Sina Bohnacker1,14
PDF (2642 KB)
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