Advances in Chikungunya Virus

Chikungunya is an infection caused by the chikungunya virus.The virus is spread between people by two types of mosquitos: Aedes albopictus and Aedes aegypti. They mainly bite during the day. The virus may circulate within a number of animals including birds and rodents. Diagnosis is by either testing the blood for the virus’s RNA or antibodies to the virus. The symptoms can be mistaken for those of dengue fever and Zika fever. After a single infection it is believed most people become immune. The best means of prevention is overall mosquito control and the avoidance of bites in areas where the disease is common. This may be partly achieved by decreases mosquitoes access to water and with the use of insect repellent and mosquito nets. There is no vaccine and no specific treatment as of 2016. Recommendations include rest, fluids, and medications to help with fever and joint pain.


In the present book, fifteen typical literatures about chikungunya virus published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, virus disease, virology, epidemiology, ect. We hope this book can demonstrate advances in chikungunya virus as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Detection of Chikungunya Virus in Saliva and Urine
  • Chapter 2
    Chikungunya Virus Capsid Protein Contains Nuclear Import and Export Signals
  • Chapter 3
    Virus Replicon Particle Based Chikungunya Virus Neutralization Assay Using Gaussia Luciferase as Readout
  • Chapter 4
    Characterization of a Chikungunya Virus Strain Isolated from Banked Patients’ Sera
  • Chapter 5
    Chikungunya Virus with E1-A226V Mutation Causing Two Outbreaks in 2010, Guangdong, China
  • Chapter 6
    Comparative Analysis of the Genome Sequences and Replication Profiles of Chikungunya Virus Isolates Within the East, Central and South African (ECSA) Lineage
  • Chapter 7
    Emergence and Potential for Spread of Chikungunya Virus in Brazil
  • Chapter 8
    Vertical Transmission of Indian Ocean Lineage of Chikungunya Virus in Aedes Aegypti and Aedes Albopictus Mosquitoes
  • Chapter 9
    Analysis of Coevolution in Nonstructural Proteins of Chikungunya Virus
  • Chapter 10
    Climate Change Effects on Chikungunya Transmission in Europe: Geospatial Analysis of Vector’s Climatic Suitability and Virus’ Temperature Requirements
  • Chapter 11
    Co-Circulation of the Dengue with Chikungunya Virus during the 2013 Outbreak in the Southern Part of Lao PDR
  • Chapter 12
    Development of a Real-Time Cell Analysing (RTCA) Method as a Fast and Accurate Screen for the Selection of Chikungunya Virus Replication Inhibitors
  • Chapter 13
    Prevalence of Dengue and Chikungunya Virus Infections in North-Eastern Tanzania: A Cross Sectional Study among Participants Presenting with Malaria-Like Symptoms
  • Chapter 14
    Suramin Is a Potent Inhibitor of Chikungunya and Ebola Virus Cell Entry
  • Chapter 15
    Long-Term Persistence of Chikungunya Virus Neutralizing Antibodies in Human Populations of North Eastern Thailand
  • Chapter 15
    Long-Term Persistence of Chikungunya Virus Neutralizing Antibodies in Human Populations of North Eastern Thailand
Readership: Students, academics, teachers and other people attending or interested in Chikungunya Virus.
Ottmar Herchenröder, Institute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, Schillingallee 69, Rostock, Germany

Beate Mareike Kümmerer, Institute of Virology, University of Bonn Medical Centre, Bonn, Germany

Karen Caiyun Chen, Department of Microbiology, Laboratory of Molecular RNA Virology and Antiviral Strategies, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore

Jan C. Semenza, European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden

Seiji Kanda, Department of Public Health, Kansai Medical University, 2-5-1, Shinmachi, Hirakata-shi, Osaka, Japan

Barbara S. Schnierle, Department of Virology, Paul-Ehrlich-Institut, Paul-Ehrlich Strasse 51-59, Langen, Germany

and more...
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