Tumor Research

Oncology is a branch of medicine that deals with the prevention, diagnosis and treatment of cancer. Cancers are best managed by discussing in multi-disciplinary tumor board where medical oncologist, surgical oncology, radiation oncology, pathologist, radiologist and organ specific oncologists meet to find the best possible management for an individual patient considering the physical, social, psychological, emotional and financial status of the patients. It is very important for oncologists to keep updated of the latest advancements in oncology as changes in management of cancer are quite common. Those who are interested in the field of oncology could read reviews and original articles in this book to gain a more systematic understanding of oncology.


In the present book, thirty typical literatures about oncology published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, oncology, genome biology, cytology, ect. We hope this book can demonstrate advances in oncology as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Tumor Heterogeneity: Next-Generation Sequencing Enhances the View from the Pathologist’s Microscope
  • Chapter 2
    Next Generation Sequencing and Tumor Mutation Profiling: Are We Ready for Routine Use in the Oncology Clinic?
  • Chapter 3
    Age Dependence of Tumor Genetics in Unfavorable Neuroblastoma: ArrayCGH Profiles of 34 Consecutive Cases, Using a Swedish 25-Year Neuroblastoma Cohort for Validation
  • Chapter 4
    A General Framework for Analyzing Tumor Subclonality Using SNP Array and DNA Sequencing Data
  • Chapter 5
    Oncogenes and Tumor Suppressor Genes: Comparative Genomics and Network Perspectives
  • Chapter 6
    Tumor Loci and Their Interactions on Mouse Chromosome 19 That Contribute to Testicular Germ Cell Tumors
  • Chapter 7
    Familial Testicular Germ Cell Tumor: No Associated Syndromic Pattern Identified
  • Chapter 8
    Integrating Genetics and Epigenetics in Breast Cancer: Biological Insights, Experimental, Computational Methods and Therapeutic Potential
  • Chapter 9
    A Joint Analysis of Metabolomics and Genetics of Breast Cancer
  • Chapter 10
    Aberrant PTPRO Methylation in Tumor Tissues as a Potential Biomarker That Predicts Clinical Outcomes in Breast Cancer Patients
  • Chapter 11
    New Concepts in Breast Cancer Genomics and Genetics
  • Chapter 12
    Obtaining Informed Consent for Clinical Tumor and Germline Exome Sequencing Oo Newly Diagnosed Childhood Cancer Patients
  • Chapter 13
    Primer on Tumor Immunology and Cancer Immunotherapy
  • Chapter 14
    Diagnosis and Treatment of Solid Pseudopapillary Tumor of the Pancreas: Experience of One Single Institution from Turkey
  • Chapter 15
    Multiple Tumor Marker Protein Chip Detection System in Diagnosis of Pancreatic Cancer
  • Chapter 16
    Serum Irisin Levels Are Lower in Patients with Breast Cancer: Association with Disease Diagnosis and Tumor Characteristics
  • Chapter 17
    A Mutation Screening of Oncogenes, Tumor Suppressor Gene TP53 and Nuclear Encoded Mitochondrial Complex I Genes in Oncocytic Thyroid Tumors
  • Chapter 18
    Tumor Phenotype and Breast Density in Distinct Categories of Interval Cancer: Results of Population-Based Mammography Screening in Spain
  • Chapter 19
    The Clinical Trial Landscape in Oncology and Connectivity of Somatic Mutational Profiles to Targeted Therapies
  • Chapter 20
    Advancing Clinical Oncology through Genome Biology and Technology
  • Chapter 21
    Evidence-Based Medicine and Clinical Fluorodeoxyglucose PET/MRI in Oncology
  • Chapter 22
    Current Concepts in Clinical Radiation Oncology
  • Chapter 23
    Scenario Drafting for Early Technology Assessment of Next Generation Sequencing in Clinical Oncology
  • Chapter 24
    Mathematical Models for Translational and Clinical Oncology
  • Chapter 25
    Associations between Clinical and Sociodemographic Data and Patterns of Communication in Pediatric Oncology
  • Chapter 26
    Contrast-Enhanced [18 F] Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography in Clinical Oncology: Tumor-, Site-, and Question-Based Comparison with Standard Positron Emission Tomography/Computed Tomography
  • Chapter 27
    Lack of Timely Accrual Information in Oncology Clinical Trials: A Cross-Sectional Analysis
  • Chapter 28
    Testing the Treatment Effect on Competing Causes of Death in Oncology Clinical Trials
  • Chapter 29
    Next Generation Sequencing and Tumor Mutation Profiling: Are We Ready for Routine Use in the Oncology Clinic?
  • Chapter 30
    Clinical Oncology in Resource-Limited Settings
Readership: Students, academics, teachers and other people attending or interested in Tumor Research
Elaine Mardis
The Genome Institute at Washington University, Washington University, School of Medicine, 4444 Forest Park Blvd, St Louis, USA

Debu Tripathy
University of Southern California, Keck School of Medicine, USC/Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, NTT-3429, Los Angeles, USA

Cihan Cetinkaya
Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden

Bo Li
Program of Bioinformatics, University of Michigan, 5940A Buhl, Box 5618, Ann Arbor, USA

Angabin Matin
Department of Genetics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA

Kenneth Miles
Department of Diagnostic Imaging Princess Alexandra Hospital, Institute of Nuclear Medicine University College London, UK

Michael Orth
Department of Radiotherapy and Radiation Oncology Ludwig-Maximilians-University of Munich, Germany

Ralf Gallasch
Biocenter, Division of Bioinformatics, Innsbruck Medical University, Innsbruck, Austria

Silvia Morbelli
PhD, Nuclear Medicine Unit, IRCCS AOU San Martino- IST, Department of Health Sciences, University of Genoa, Genoa, Italy

Franco M. Buonaguro
Division of Molecular Biology & Viral Oncology, Department of Experimental Oncology Istituto Nazionale Tumori -IRCCS “Fond Pascale”, France

and more...
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