Advances in Ebola Virus

Ebola virus, formerly designated Zaire ebolavirus, is one of five known viruses within the genus Ebola virus. Four of the five known Ebola viruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals, were known as Ebola virus disease (EVD). Ebola virus has caused the majority of human deaths from EVD, and is the cause of the 2013–2015 Ebola virus epidemic in West Africa, which has resulted in at least 28,657 suspected cases and 11,325 confirmed deaths. Ebola virus is a zoonotic pathogen. Intermediary hosts have been reported to be "various species of fruit bats...throughout central and sub-Saharan Africa". Evidence of infection in bats has been detected through molecular and serologic means. However, Ebola viruses have not been isolated in bats. End hosts are humans and great apes, infected through bat contact or through other end hosts. Ebola virus outbreaks tend to occur when temperatures are lower and humidity is higher than the usual for Africa.

 

In the present book, fourteen typical literatures about diabetes Ebola virus published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, virology, epidemiology, ect. We hope this book can demonstrate advances in Ebola virus as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Ebola, the Killer Virus
  • Chapter 2
    Human Ebola Virus Infection in West Africa: A Review of Available Therapeutic Agents That Target Different Steps of the Life Cycle of Ebola Virus
  • Chapter 3
    Can Ebola Virus Become Endemic in the Human Population?
  • Chapter 4
    Insight into the Ebola Virus Nucleocapsid Assembly Mechanism: Crystal Structure of Ebola Virus Nucleoprotein Core Domain at 1.8 Å Resolution
  • Chapter 5
    The Ebola Contagion and Forecasting Virus: Evidence from Four African Countries
  • Chapter 6
    Rapid Assessment of Knowledge, Attitudes, Practices, and Risk Perception Related to the Prevention and Control of Ebola Virus Disease in Three Communities of Sierra Leone
  • Chapter 7
    Ebola Virus Disease and the Veterinary Perspective
  • Chapter 8
    Ebola Virus Disease Complicated with Viral Interstitial Pneumonia: A Case Report
  • Chapter 9
    Transmission Dynamics and Control of Ebola Virus Disease (EVD): A Review
  • Chapter 10
    Repurposed Therapeutic Agents Targeting the Ebola Virus: A Protocol for a Systematic Review
  • Chapter 11
    Suramin Is a Potent Inhibitor of Chikungunya and Ebola Virus Cell Entry
  • Chapter 12
    In Vivo Ebola Virus Infection Leads to a Strong Innate Response in Circulating Immune Cells
  • Chapter 13
    Recombinant Lentogenic Newcastle Disease Virus Expressing Ebola Virus GP Infects Cells Independently of Exogenous Trypsin and Uses Macropinocytosis as the Major Pathway for Cell Entry
  • Chapter 14
    Elucidating Variations in the Nucleotide Sequence of Ebola Virus Associated with Increasing Pathogenicity
Readership: Students, academics, teachers and other people attending or interested in Ebola Virus
Kang Yiu Lai
Department of Intensive Care, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR, China.

Hakan Leblebicioglu
Department of Infectious Diseases and Clinical Microbiology, Medical School, Ondokuz Mayis University, Samsun, Turkey.

Nicola Petrosillo
National Institute for Infectious Diseases Lazzaro Spallanzani-INMI IRCCS, Rome, Italy

Gerardo Chowell
School of Human Evolution and Social Change, Arizona State University, Tempe, USA

Hussein Sweiti
Public Health, University Hospital Düsseldorf, Düsseldorf, Germany

Roger Hewson
Public Health England, Porton Down, Salisbury, UK

and more...
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