Advances in Stem Cell

Stem cells are undifferentiated biological cells that can differentiate into specialized cells and can divide (through mitosis) to produce more stem cells. They are found in multi-cellular organisms. In mammals, there are two broad types of stem cells: embryonic stem cells, which are isolated from the inner cell mass of blastocysts, and adult stem cells, which are found in various tissues. In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenishing adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells—ectoderm, endoderm and mesoderm—but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues. Adult stem cells are frequently used in various medical therapies (e.g., bone marrow transplantation). Stem cells can now be artificially grown and transformed into specialized cell types with characteristics consistent with cells of various tissues such as muscles or nerves.

 

In the present book, thirteen typical literatures about stem cell published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, biotechnology, cell biology, cytology, ect. We hope this book can demonstrate advances in stem cell as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Biobanking Human Embryonic Stem Cell Lines: Policy, Ethics and Efficiency
  • Chapter 2
    Translating Stem Cell Research to the Clinic: A Primer on Translational Considerations for Your First Stem Cell Protocol
  • Chapter 3
    Clinical Trials for Stem Cell Transplantation: When Are They Needed?
  • Chapter 4
    Human Pluripotent Stem Cell Process Parameter Optimization in a Small Scale Suspension Bioreactor
  • Chapter 5
    Curcumin as a Double-Edged Sword for Stem Cells: Dose, Time and Cell Type-Specific Responses to Curcumin
  • Chapter 6
    Large-Scale Cell Production of Stem Cells for Clinical Application Using the Automated Cell Processing Machine
  • Chapter 7
    Techniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell Derivation
  • Chapter 8
    Single-Cell Analysis Reveals Key Roles for Bcl11a in Regulating Stem Cell Fate Decisions
  • Chapter 9
    Transplantation of Induced Pluripotent Stem Cell‑Derived Renal Stem Cells Improved Acute Kidney Injury
  • Chapter 10
    L-Asparaginase-Based Regimens Followed by Allogeneic Hematopoietic Stem Cell Transplantation Improve Outcomes in Aggressive Natural Killer Cell Leukemia
  • Chapter 11
    Adipose Tissue-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma: Stem Cell Transplantation Methods That Enhance Stemness
  • Chapter 12
    Establishment of a Pancreatic Stem Cell Line from Fibroblast-Derived Induced Pluripotent Stem Cells
  • Chapter 13
    Physical Exercise Training versus Relaxation in Allogeneic Stem Cell Transplantation (PETRA Study) – Rationale and Design of a Randomized Trial to Evaluate a Yearlong Exercise Intervention on Overall Survival and Side-Effects after Allogeneic Stem Cell Transplantation
Readership: Students, academics, teachers and other people attending or interested in Stem Cell.
Søren Holm
Centre for Social Ethics and Policy, School of Law, University of Manchester, Manchester M13 9PL, UK

Timothy O’Brien
Regenerative Medicine Institute, National University of Ireland, Galway, Ireland

Yonatan Y. Lipsitz
Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

Daisuke Kami
Department of Regenerative Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan

Jarosław Lewandowski
Department of Reproductive Biology and Stem Cells, Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland

Morikuni Tobita
Department of Plastic and Reconstructive Surgery, Juntendo University School of Medicine, Tokyo, Japan

and more...
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