Advances in Epilepsy Therapy

Epilepsy is a group of neurological diseases characterized by epileptic seizures. The cause of most cases of epilepsy is unknown, although some people develop epilepsy as the result of brain injury, stroke, brain tumors, infections of the brain, and birth defects. Known genetic mutations are directly linked to a small proportion of cases. The mainstay treatment of epilepsy is anticonvulsant medications, possibly for the person’s entire life. The choice of anticonvulsant is based on seizure type, epilepsy syndrome, other medications used, other health problems, and the person’s age and lifestyle. Epilepsy usually cannot be cured, but medication can control seizures effectively in about 70% of cases. There are a number of medications available. Phenytoin, carbamazepine and valproate appear to be equally effective in both partial and generalized seizures.

 

In the present book, twelve typical literatures about epilepsy therapy published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, genetics, neurology, etc. We hope this book can demonstrate advances in epilepsy therapy as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Epilepsy and Anesthesia
  • Chapter 2
    Advancing Epilepsy Genetics in the Genomic Era
  • Chapter 3
    Clinical Characteristics of Epilepsy of Unknown origin in the Rottweiler Breed
  • Chapter 4
    Workshop on Neurobiology of Epilepsy Appraisal: New Systemic Imaging Technologies to Study the Brain in Experimental Models of Epilepsy
  • Chapter 5
    Novel Approaches to Epilepsy Treatment
  • Chapter 6
    Personalized Medicine Approaches in Epilepsy
  • Chapter 7
    Antiepileptic Drugs’ Tolerability and Safety – A Systematic Review and Meta-Analysis of Adverse Effects in Dogs
  • Chapter 8
    Impact of a Pharmaceutical Care Programme on Health-Related Quality of Life among Women with Epilepsy: A Randomised Controlled Trial (IPHIWWE Study)
  • Chapter 9
    Peritumoral Epilepsy: Relating form and Function for Surgical Success
  • Chapter 10
    Epilepsy Surgery of Dysembryoplastic Neuroepithelial Tumors Using Advanced Multitechnologies with Combined Neuroimaging and Electrophysiological Examinations
  • Chapter 11
    Potential Effects of Valproate and Oxcarbazepine on Growth Velocity and Bone Metabolism in Epileptic Childrena Medical Center Experience
  • Chapter 12
    Novel Way to Investigate Evolution of Children Refractory Epilepsy by Complexity Metrics in Massive Information
Readership: Students, academics, teachers and other people attending or interested in Epilepsy Therapy.
Heather C. Mefford
Department of Pediatrics, Division of Genetic Medicine, University of Washington, Seattle, USA

Linda Heske
Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine Biosciences, Norwegian University of Life Sciences, Oslo, Norway

Jerome Engel
Jr. Department of Neurology, Neurobiology, and Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

L. E. Walker
Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK

Marios Charalambous
Faculty of Brain Sciences, UCL Institute of Neurology, University College London, London, UK

Mark O. Cunninghamb
Institute of Neuroscience, The Medical School, Framlington Place, Newcastle University, Newcastle upon Tyne, UK

and more...
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