[1]
|
Goldstein, J. L., Hobbs, H. H., and Brown, M. S., (2001) Familial hypercholesterolemia, The Metabolic and Molecular Basis of Inherited Disease, Scriver CR, Beaudet, A. L., Sly, W. S., Valle D, eds., McGraw-Hill, New York, 2863?2913.
|
[2]
|
Ross, R., (1999) Atherosclerosis: An inflammatory disease, N. Engl. J. Med., 340, 115?126.
|
[3]
|
Civeira, F., (2004) Guidelines for the diagnosis and management of heterozygous familial hypercholestero- lemia, Atherosclerosis, 173, 55?68.
|
[4]
|
Kern, F., (1990) Cholesterol metabolism, LDL, and the LDL receptor, Edited by Myant NB, Academic press, NewYork, 465.
|
[5]
|
Shoji, T., Nishizawa, Y., Fukumoto, M., Shimamura, K., Kimura J., Kanda, H., et al., (2000) Inverse relationship between circulating oxidized low density lipoprotein (oxLDL) and anti-oxLDL antibody levels in healthy subjects. Atherosclerosis; 148, 171?7.
|
[6]
|
Bertolini, S., Cantafora, A., Averna, M., Cortese, C., Motti, C., Martini, S., et al., (2000) Clinical expression of familial hypercholesterolemia in clusters of mutations of the LDL receptor gene that cause a receptor-defective or receptor-negative phenotype, Arterioscler Thromb Vasc Biol, 20, 41?52.
|
[7]
|
Hollak, C. E., van Weely, S., van Oers, M. H., and Aerts, J. M., (1994) Marked elevation of plasma chitotriosidase activity, A novel hallmark of Gaucher disease, J. Clin. Invest., 93, 1288?1292.
|
[8]
|
Boot, R. G., van Achterberg, T. A., van Aken, B. E., Renkema, G. H., Jacobs, M. J., Aerts, J. M., et al., (1999) Strong induction of members of the chitinase family of proteins in atherosclerosis: Chitotriosidase and human cartilage gp-39 expressed in lesion macrophages, Arterio- scler Thromb Vasc Biol, 19, 687?694.
|
[9]
|
Malaguarnera, L., Di Rosa, M., Zambito, A. M., dell'Ombra, N., Nicoletti, F., and Malaguarnera, M., (2006) Chitotrio- sidase gene expression in Kupffer cells from patients with non- alcoholic fatty liver disease, Gut, 55, 1313?1320.
|
[10]
|
Artieda, M., Cenarro, A., Ga?án, A., Jericó, I., Gonzalvo, C., Casado, J. M., et al., (2003) Serum chitotriosidase activity is increased in subjects with atherosclerosis disease, Arterioscler Thromb Vasc Biol., 23, 1645?1652.
|
[11]
|
Artieda, M., Cenarro, A., Ga?án, A., Lukic, A., Moreno, E., Puzo, J., et al., (2007) Serum chitotriosidase activity, a marker of activated macrophages, predicts new cardiovascular events independently of C-Reactive Protein, Cardiology, 108, 297?306.
|
[12]
|
Hansson, G. K., (2005) Inflammation, atherosclerosis, and coronary artery disease, N. Engl. J. Med., 352, 1685?1695.
|
[13]
|
van Eijk, M., van Roomen, C. P., Renkema, G. H., Bussink, A. P., Andrews, L., Blommaart, E. F., et al., (2005) Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity, Int. Immunol., 17, 1505?12.
|
[14]
|
Shaw, P. X., H?rkk?, S., Tsimikas, S., Chang, M. K., Palinski, W., Silverman, G. J., et al., (2001) Human-derived anti-oxidized LDL autoantibody blocks uptake of oxi- dized LDL by macrophages and localizes to atheroscle- rotic lesions in vivo, Arterioscler Thromb Vasc Biol, 21, 1333?9.
|
[15]
|
Bláha, M., Cermanová, M., Bláha, V., Blazek, M., Maly, J., Siroky, O., et al., (2007) Safety and tolerability of long lasting LDL-apheresis in familial hyperlipopro- teinemia. Ther Apher Dial, 11, 9?15.
|
[16]
|
Hixson, J. E. and Vernier, D. T., (1990) Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI, J. Lipid. Res., 31, 545–8.
|
[17]
|
Tsukamoto, K., Watanabe, T., Matsushima, T., Kinoshita, M., Kato, H., Hashimoto, Y., Kurokawa, K., and Teramoto, T., (1993) Determination by PCR-RFLP of apo E genotype in a Japanese population, J. Lab. Clin. Med., 121, 598?602.
|
[18]
|
Hulthe, J., Wikstrand, J., Lidell, A., Wendelhag, I., Hansson, G. K., and Wiklund, O., (1998) Antibody titers against oxidized LDL are not elevated in patients with familial hypercholesterolemia, Arterioscler Thromb Vasc Biol, 18, 1203?1211.
|
[19]
|
Tinahones, F. J., Gomez-Zumaquero, J. M., Rojo- Martinez, G., Cardona, F., Esteva de Antonio, I. E., Ruiz de Adana, M. S., et al., (2002) Increased levels of anti-oxidized low-density lipoprotein antibodies are associated with reduced levels of cholesterol in the general population, Metabolism, 51, 429?31.
|
[20]
|
Tinahones, F. J., Gomez-Zumaquero, J. M., Garrido- Sanchez, L., Garcia-Fuentes, E., Rojo-Martinez, G., Esteva, I., et al., (2005) Influence of age and sex on levels of anti-oxidized LDL antibodies and anti-LDL immune complexes in the general population, J. Lipid. Res., 46, 452?7.
|
[21]
|
Canudas, J., Cenarro, A., Civeira, F., García-Otín, A. L., Arístegui, R., Díaz, C., et al., (2001) Chitotriosidase genotype and serum activity in subjects with combined hyperlipidemia: Effect of the lipid-lowering agents, atorvastatin and bezafibrate, Metabolism, 50, 447?450.
|
[22]
|
Brizzi, P., Tonolo, G., Bertrand, G., Carusillo, F., Severino, C., Maioli, M., et al., (2004) Autoantibodies against oxidized low-density lipoprotein (oxLDL) and LDL oxidation status, Clin. Chem. Lab. Med., 42, 164?70.
|
[23]
|
Frosteg?rd, J., Tao, W., Georgiades, A., R?stam, L., Lindblad, U., and Lindeberg, S., (2007) Atheroprotective natural anti-phosphorylcholine antibodies of IgM subclass are decreased in Swedish controls as compared to non-westernized individuals from New Guinea, Nutr Metab (Lond), 20, 7.
|
[24]
|
Binder, C. J., Chang, M. K., Shaw, P. X., Miller, Y. I., Hartvigsen, K., Dewan, A., et al., (2002) Innate and acquired immunity in atherogenesis, Nat. Med., 8, 1218–26.
|
[25]
|
Palinski, W., Miller, E., Witztum, J. L., (1995) Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis, Proc. Natl. Acad. Sci., USA, 92, 821–5.
|
[26]
|
Binder, C. J., H?rkk?, S., Dewan, A., Chang, M. K., Kieu, E. P., Goodyear, C. S., et al., (2003) Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL, Nat. Med., 9, 736–43.
|
[27]
|
Ameli, S., Hultgardh-Nilsson, A., Regnstrom, J., Calara, F., Yano, J., Cercek, B., et al., (1996) Effect of immu- nization with homologous LDL and oxidized LDL on early atherosclerosis in hypercholesterolemic rabbits, Arteri-oscler Thromb Vasc Biol, 16, 1074–9.
|
[28]
|
Pappalardo, F., Musumeci, S., and Motta, S., (2008) Modeling immune system control of atherogenesis, Bioinformatics.
|
[29]
|
Orem, C., Orem, A., Uydu, H. A., Celik, S., Erdol, C., and Kural, B. V., (2002) The effects of lipid-lowering therapy on low-density lipoprotein auto-antibodies: Relationship with low-density lipoprotein oxidation and plasma total antioxidant status, Coron Artery Dis, 13, 65–71.
|
[30]
|
Brizzi, P., Isaja, T., D'Agata, A., Malaguarnera, L., Malaguarnera, M., and Musumeci, S., (2002) Oxidized LDL antibodies (OLAB) in patients with beta thala- ssemia major, J. Atheroscler Thromb, 9, 139?44.
|