A. J. Carter, M. R. Adams, M. J. Woodward and R. M. La Ragione, “Control Strategies for Salmonella Colonization of Poultry: The Probiotic Perspective,” Food Science and Technology, Vol. 5, No. 5, 2009, pp. 103-115.

has been cited by the following article:

• TITLE: The Effect of a Lactobacillus-Based Probiotic for the Control of Necrotic Enteritis in Broilers

  AUTHORS: Sherryll Lynn Layton, Xochitl Hernandez-Velasco, Shivaramaiah Chaitanya, Jorge Xavier, Anita Menconi, Juan David Latorre, Gopala Kallapura, Vivek Ayamchirakkunnel Kuttappan, Ross Elderon Wolfenden, Raphael Lucio Andreatti Filho, Billy Marshal Hargis, Guillermo Téllez

  KEYWORDS: Lactobacillus; Necrotic Enteritis; Salmonella; Coccidiosis; Probiotic

  JOURNAL NAME: Food and Nutrition Sciences, Vol.4 No.11A, November 1, 2013

  ABSTRACT: Necrotic Enteritis (NE) caused by Clostridium perfringens (CP) in poultry is probably the most important bacterial disease in terms of economic implications. The disease is multi-factorial and is invariably associated with predisposing factors. The present study investigated the effect of a commercially available Lactobacillus-based probiotic (FM-B11) for the control of necrotic enteritis in broiler chickens. In experiment 1, one-day-of-hatch broiler chicks were randomly allocated to the following treatment groups: 1) Non-challenged (NC); 2) Challenged (C); 3) Challenged + probiotic (C+ FM-B11). Prior to placement, chicks in groups 2 and 3 received 0.25 mL of Salmonella typhimurium (ST) containing 105 cfu of viable cells by oral gavage. At 14, 15 and 16 days of age, all chicks in group 3 were treated with FM-B11 in the drinking water at a concentration of 106 cfu/ml. At 21d of age, all chicks in groups 2 and 3, were individually challenged with 5 × 104 sporulated oocysts of E. maxima by oral gavage. At 26d of age, all chicks in groups 2 and 3, were individually challenged with 108 cfu CP; body weight (BW) was recorded prior to challenge. The experiment was terminated at 29 days of age and the following parameters were evaluated: NE-associated mortality, CP lesion scores, CP concentrations in ileum, BW, and body weight gain (BWG). Chicks treated with FM-B11 had significantly (P 0.05) difference in lesion score between C and C + FM-B11, group C + FM-B11 had significantly (P Lactobacillus-based probiotic FM-B11 was able to reduce the severities of NE, as a secondary bacterial infection, in an experimental NE challenge model; as well as, in a commercial field outbreak of NE.