TITLE:
Current Methods of Human and Animal Brucellosis Diagnostics
AUTHORS:
Ekaterina A. Smirnova, Andrey V. Vasin, Nurlan T. Sandybaev, Sergey A. Klotchenko, Marina A. Plotnikova, Olga V. Chervyakova, Abylai R. Sansyzbay, Oleg I. Kiselev
KEYWORDS:
Brucellosis; Diagnostics; Bacteriology; Polymerase Chain Reaction; Serology
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.3 No.3,
August
28,
2013
ABSTRACT:
Brucellosis
is an urgent infectious disease of livestock and wild animals and the commonest
human zoonosis. Diagnosis of brucellosis is rather complicated and it has to be
obligatorily confirmed by
laboratory testing. Direct bacteriological and molecular methods and indirect
serological tests are used for brucellosis diagnostics. The choice of the
diagnostic tools depends on the overall epidemiological situation in the region
and the objectives of the study: validation of the diagnosis, screening
(monitoring), cross-sectional studies or confirmation of brucellosis-free
status of the region. The review describes current bacteriological, serological
and molecular methods, routinely used for the diagnosis of brucellosis in
humans and animals. The perspectives of brucellosis diagnostics are also
discussed.