TITLE:
Ionic Liquid-Based Ultrasound-Assisted Emulsification Microextraction Coupled with HPLC for Simultaneous Determination of Glucocorticoids and Sex Hormones in Cosmetics
AUTHORS:
Xiaoji Cao, Lingxiao Shen, Xuemin Ye, Feifei Zhang, Jiaoyu Chen, Weimin Mo
KEYWORDS:
Ionic Liquid; Ultrasound-Assisted Emulsification Microextraction; Hormones; Cosmetics; High Performance Liquid Chromatography
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.3 No.2A,
May
27,
2013
ABSTRACT:
An effective and environmentally friendly method based on ionic liquid-based ultrasound-assisted
emulsification microextraction(IL-USAEME) and high performance
liquid chromatography (HPLC) has been developed for the determination
of nine hormones including three glucocorticoids, one androgen and five progestogens
in cosmetics. Several factors that affect the extraction efficiency, such as
the kinds and volume of ionic liquid, salt concentration, ultrasonic power and
time, and centrifugation time were investigated and optimized. Under the
optimum extraction condition, the recoveries of analytes ranged from 85.97% to 108.84%
except prednisolone (62.30%). The intraday and interday precision was below
2.51% and 3.30%, respectively.