C. S. Freitas, C. H. Baggio, J. E. Da Silva-Santos, L. Rieck, C. A. de Moraes Santos, C. C. Júnior, L. C. Ming, D. A. Garcia Cortez and M. C. Marques, “Involvement of Nitric Oxide in the Gastroprotective Effects of an Aqueous Extract of Pfaffia glomerata (Spreng) Pedersen, Amaranthaceae in Rats,” Life Sciences, Vol. 74, No. 9, 2004, pp. 1167-1179. doi:10.1016/j.lfs.2003.08.003

has been cited by the following article:

• TITLE: Use of SFC in Extraction of Adaptogens from Brazilian Plants

  AUTHORS: Marcelle Fernanda Carulo

  KEYWORDS: Chromatography; Supercritical; Extraction; Plants; Adaptogens

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.3 No.12A, December 31, 2012

  ABSTRACT: Bioactive substances found in plants are very interesting because of their importance in medicine and foods. Species of Pfaffia genre is common in Brazil, the largest center of collection of this species. Statistics report that 11,000 tons of roots and other plants were exported in 2011. Due to the large market demand, a growth of 10% per year is estimated. One of the promising areas of study involves the supercritical fluid extraction of active compounds present in plants. The current goal is to reduce dependence on foreign markets. The extraction of bioactive compound known as Beta-Ecdysone has been studied. Statistics show that profits of exports coming from the raw material is almost ten times smaller than the extract itself. Considering this fact, we emphasize the importance of an alternative method of industrial extraction in Brazil using supercritical technology, which proves to be environmentally safe.