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C. Lipinski and A. Hopkins. “Navigating Chemical Space for Biology and Medicine”, Nature, Vol. 432, 2004, pp. 855-861. (b) S. L. Schreiber, “Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery,” Science, Vol. 287, No. 5460, 2000, pp. 1964-1969. doi:10.1126/science.287.5460.1964

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