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has been cited by the following article:

• TITLE: Biofilm Formation by Streptococcus mutans and Related Bacteria

  AUTHORS: Junko Nishimura, Tadao Saito, Hiroshi Yoneyama, Lan Lan Bai, Kazuhiko Okumura, Emiko Isogai

  KEYWORDS: Caries; Streptococcus mutans; Streptococcus sobrinus; Biofilm; Exocellular Polysaccharide; Glucan; Glucosyltransferase

  JOURNAL NAME: Advances in Microbiology, Vol.2 No.3, September 24, 2012

  ABSTRACT: Caries is a disease of human dentition characterized by the loss of mineralized surfaces of the tooth; it is an infectious disease of the oral cavity in which biofilms play a causative role. Control of biofilms has traditionally relied on non-specific removal of plaque by mechanical means such as brushing, although it is difficult to remove biofilms by this method. Caries is also a widespread infection in children. Streptococcus mutans and S. sobrinus are important causative agents of caries. They produce a homologous exocellular polysaccharide called glucan, which strongly adheres to the enamel surface. This is a review of oral microbial biofilm formation by S. mutans and other related bacteria.