Article citationsMore>>
Fujiwara, T., Kubota, K., Sato, T., Matsuzawa, T., Tada, M., Iwata, R., Itoh, M., Hatazawa, J., Sato, K., Fakuta, H. and Ido, T. (1990) N-[18F]Fluoroacetyl Glucosamine: A Potential Agent for Cancer Diagnosis. Journal of Nuclear Medicine, 31, 1654-1658.
has been cited by the following article:
-
TITLE:
Synthesis of 4-[F-18]Fluoro-4-Deoxy-N-Acetyl-1,3,6-Tri-O-Acetylglucosamine, a Potential Brain Imaging PET Agent
AUTHORS:
Murthy Akula, Derek Cressy, Lee Collier, George Kabalka, Dustin Osborne
KEYWORDS:
N-Acetylglucosamine, Amyloidogenesis, Lipase-Candida rugosa
JOURNAL NAME:
Natural Science,
Vol.16 No.3,
March
29,
2024
ABSTRACT: The synthesis of a promising brain imaging agent 4-[F-18]fluoro-4-deoxy-N-acetyl-1,3,6-tri-O-acetylglucosamine, 2, was successfully accomplished from commercially available N-acetyl glucosamine in 5 steps. The non-decay corrected radiochemical yield and purity were found to be 31% ± 4% (n = 3) and >98% respectively. The total reaction time for radio labelling step was 50 min.