TITLE:
Prevelance of Bovine Cysticercosis in Egypt and the Cysticidal Effect of Two Extracts Obtained from Balanites aegyptiaca and Moringa oleifera on Mice Model Affected with T. saginata Cysticerci
AUTHORS:
Omnia M. Kandil, Noha M. F. Hassan, Doaa Sedky, Hatem A. Shalaby, Heba M. Ashry, Nadia M. T. Abu El Ezz, Sahar M. Kandeel, Mohamed S. Abdelfattah, L. Ying, Ebtesam M. Al-Olayan
KEYWORDS:
Prevalence, Balanites aegyptiaca, Moringa oleifera, Mice, T. saginata Cysticerci
JOURNAL NAME:
Open Journal of Animal Sciences,
Vol.14 No.2,
March
11,
2024
ABSTRACT: The aim
of the present study was to determine the prevalence of bovine cysticercosis in
both cattle and buffloas, in Egypt and to assess the cysticidal efficacy of Balanites
aegyptiaca fruits (B. aegyptiaca) and Moringa oleifera seeds (M. oleifera)
extracts in experimentally infected mice. The study detected the level of tumor
necrosis factor (TNF-α) to monitor the
immune and inflammatory responses of experimentally infected mice. Through meat
inspection, a total number of 2125 male bovine, 2 to 5 years old, (1125 cattle and
1000 buffloes) were examined under the authority of Albsatine and Alwaraq official
abattoirs in Cairo Governorate, Egypt covering the period extended from March 2022
to April 2023. The overall
prevalence of the disease among bovine was 7.8% (6.31% of cattle and 9.5% of buffloes).
Besides, B. aegyptiaca and M. oleifera extracts showed cysticidal
activity in experimentally infected mice. A decrease in the numbers of cysticerci
was found in all treated mice groups, and up to 88% reduction was achieved in the B. aegyptiaca-treated group; higher than that was recorded in both M.
oleifera (72.23%) and albendazole-treated ones (80.56%). Postmortem findings
proved that M. oleifera and B. aegyptiaca reduced cysticerci numbers
comparable to a commercial anthelmintic. The study showed a significant decrease (P 0.001) in TNF-α levels after treatment with Balanites and Moringa extracts, compared with the untreated control and the albendazole-treated
groups.