Annadatha, A., Talwar, D., Acharya, S., Kumar, S. and Lahane, V. (2021) Acute Chest Syndrome, Avascular Necrosis of Femur, and Pulmonary Embolism All at Once: An Unexpected Encounter in the First-Ever Admission of a Sickle Cell Patient. Cureus, 13, e17656. https://doi.org/10.7759/cureus.17656 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8489536/

has been cited by the following article:

• TITLE: Acute Chest Syndrome and Pulmonary Embolism in Sickle Cell Disease Case Report: About one Case Admitted at the Mixed Medecine and Sickle Cell Anemia Center (M.M.SC.A) Kinshasa in the Democratic Republic of the Congo

  AUTHORS: Alain Munganga Mukuna, Mawisa Nkemfuni Timothée, Longina Kake Roger, Ndalako Yagbanzi Noela, Vangu Payadu Christian, Nimy-Ta-Phemba Tany, Ikoko Mpembe Mimie, Kabengele Obel Benoit

  KEYWORDS: Acute Chest Syndrome, Pulmonary Embolism, Sickle Cell Disease

  JOURNAL NAME: Open Access Library Journal, Vol.11 No.1, January 31, 2024

  ABSTRACT: Sickle cell disease (SCD), a hereditary genetic disorder marked by abnormal circulating hemoglobin, presents a spectrum of complications necessitating collaboration among hematologists, internists, and emergency and resuscitation physicians. Chief among these complications are vaso-occlusive crises and acute thoracic syndrome, with pulmonary embolism (PE) emerging as a critical and potentially fatal manifestation. In the pediatric SCD population, the incidence of PE is likely underestimated, and documented cases are infrequent. Furthermore, clinical symptoms may overlap with those of acute chest syndrome. This paper details the case of a 22-year-old adult with SCD admitted for chest pain, respiratory distress, and rales. Pulmonary angiography revealed bilateral pulmonary emboli, primarily distal to the right pulmonary artery. Despite attempts to conduct an etiological assessment for venous thrombosis, it proved inconclusive. The patient exhibited swift improvement following the initiation of anticoagulant therapy.