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has been cited by the following article:

• TITLE: Can the Glucose Central Control System Dysfunctions Induce Diabetes Mellitus?

  AUTHORS: Altair S. de Assis, João Luiz P. da Nobrega

  KEYWORDS: Brain, Hypothalamus, CNS—Central Nervous System, Sensor Neuron Circuits, Glucose Central Control System, External Noxious Elements, Juvenile Persistent Hyperglycemia, Diabetes Mellitus, Homeostasis, Euglycemia

  JOURNAL NAME: Open Journal of Endocrine and Metabolic Diseases, Vol.13 No.12, December 29, 2023

  ABSTRACT: We study afresh how the glucose control system anomalies impact the organicity of the glucose homeostasis and build up events of persistent hyperglycemia and diabetes mellitus. We have used critically the state of art literature related to the subject, in order to cross, to compare, and to organize the relevant contents to create a logical and consistent support to the finds. We show that it is consistent to assume that persistent hyperglycemia and diabetes mellitus can have precursors not only in pancreas, but also in brain, mainly induced by noxious dysfunctions of hypothalamus sensor neurons circuits and external noxious elements, causing pancreas overload, and the consequent exhaustion—overburden.