TITLE:
Factor VII Deficiency: A Rare Cause of Severe Bleeding Disorder in a Newborn
AUTHORS:
Hanane Hajaj, Hanae Bahari, Anass Ayyad, Sahar Messaoudi, Rim Amrani
KEYWORDS:
Congenital Deficiency, Factor VII, Hemorrhage
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.13 No.6,
November
14,
2023
ABSTRACT: Factor VII deficiency is rare. It is an autosomal recessive inherited
disease with an estimated prevalence of 1/1,000,000. We report the case of a
newborn male from first-degree consanguineous parents admitted at 15 days of
life due to a hemorrhagic syndrome. Hemostasis tests showed low prothrombin
time (PT) and normal activated partial thromboplastin time (aPTT). A
coagulation panel revealed isolated factor VII deficiency. In this case, we
highlight the clinical, biological, and therapeutic aspects of this condition
during the neonatal period.