Article citationsMore>>
Geerlings, P., Chamorro, E., Chattaraj, P.K., Proft, F.D., Gázquez, J.L., Liu, S., Morell, C., Toro-Labbé, A., Vela, A. and Ayers, P. (2020) Conceptual Density Functional Theory: Status, Prospects, Issues. Theoretical Chemistry Accounts, 139, Article No. 36.
https://doi.org/10.1007/s00214-020-2546-7
has been cited by the following article:
-
TITLE:
Computational Chemistry and Molecular Modeling Techniques for the Study of Micropeptin EI-964: Insights into Its Chemical Reactivity and Potential Pharmaceutical Properties
AUTHORS:
Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik
KEYWORDS:
Micropeptin EI-964, Chemical Reactivity, Conceptual DFT, Computational Pharmacokinetics, Pharmaceutical Drugs
JOURNAL NAME:
Computational Molecular Bioscience,
Vol.13 No.3,
September
13,
2023
ABSTRACT: Micropeptin EI-964 is a cyclic peptide compound isolated from a marine cyanobacterium with potent inhibitory activity against serine proteases, particularly chymotrypsin and trypsin. It has shown promising activity against various cancer cell lines, making it a candidate for drug development. The unique structure and activity of Micropeptin EI-964 make it a promising lead compound for the development of novel serine protease inhibitors and anti-cancer drugs. Computational Chemistry and Molecular Modeling techniques can provide valuable insights into the chemical reactivity and pharmaceutical properties of Micropeptin EI-964, guiding the design and development of new compounds with enhanced bioactivity and improved drug-like properties.
Related Articles:
-
Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
-
Mirwais Rashid
-
Juan Frau, Norma Flores-Holguín, Daniel Glossman-Mitnik
-
Affoué Lucie Bédé, Amon Benjamine Assoma, Kicho Denis Yapo, Mamadou Guy-Richard Koné, Soleymane Koné, Mawa Koné, Boka Robert N’Guessan, El-Hadji Sawaliho Bamba
-
Norma Flores-Holguín, Juan Frau, Daniel Glossman-Mitnik