TITLE:
Ankylosing Spondylitis in a West African Hospital
AUTHORS:
Abdoulaye Barry, Oumar Diouhé Bah, Adama Bah, Mamadou Lamine Diallo, Kaba Condé, Samba Frein Condé, Aly Badra Kamissoko
KEYWORDS:
Ankylosing Spondylitis, Rheumatology, Ignace Deen, Guinea
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.13 No.1,
February
8,
2023
ABSTRACT: Introduction: Ankylosing spondylitis (AS) is an inflammatory rheumatic disease
characterized by predominant axial and peripheral (enthesitis, sacroiliitis)
involvement affecting young subjects aged 30 to 40 years, 80% to 98% of cases
are associated with HLA-B27. Objective: To determine the epidemiological
profile of ankylosing spondylitis in the rheumatology department of the Ignace
Deen National Hospital in Conakry (Guinea). Materials and Methods: This was a descriptive cross-sectional study carried out within the said
department over a period of 18 months from July 1, 2018 to December 31, 2020,
including all patients seen in consultation and/or hospitalized in the
department in which the diagnosis of ankylosing spondylitis had been retained
according to the modified New York criterion. The parameters studied were
sociodemographic, clinical, paraclinical and therapeutic. Result: We
collected 73 cases or 4.1% of ankylosing spondylitis out of a total of 1781
patients seen during the study period. The male gender was represented with
54.8% for a sex ratio of 1.2 M/F. The average age of our patients was 32.18 ±
12.44 years with extremes ranging from 17 to
54 years. Axial involvement was present in 89.9% of cases with a lumbar
predominance (95.2%), followed by the sacroiliac seat (35.5%), cervical (14.5%)
and dorsal at 4.8%. The pain was chronic in 93.2% of cases. The most common
drug treatment was taking analgesics and NSAIDs (100%) followed by cortisone
infiltration (41.1%), corticosteroids (30%), and physiotherapy (21.9%). Ankylosing
spondylitis represents 83% of spondyloarthritis followed by undifferentiated spondyloarthritis (9.1%)
and juvenile spondylitis (3.4%) were the most common
conditions.