TITLE:
Unilateral Ptosis in a Child with Wilm’s Tumor Induced by Vincristine
AUTHORS:
Aziza El Ouali, Karim Lahrache, Zohair El Haddar, Ayad Ghannam, Abdeladim Babakhouya, Maria Rkain, Noufissa Benajiba
KEYWORDS:
Wilms’ Tumor, Vincristine, Neuropathy, Ptosis
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.13 No.12,
December
28,
2022
ABSTRACT: Vincristine is a chemotherapy drug belonging to the group of Vinca
alkaloids which also includes vinblastine and vindesine. It is used in
hematological malignancies and solid tumors.
The Vinca alkaloids are neurotoxic, usually causing peripheral
neuropathy, and rarely cranial neuropathies. We report a case of a 33-month-old male child diagnosed with Wilms’ tumor, who had an isolated unilateral right ptosis following vincristine,
with a good improvement after stopping it.