TITLE:
Pre- and Post-Surgical Health-Related Quality of Life Evaluation of Esophageal Carcinoma Patients
AUTHORS:
Lihong Qiu, Tianzhen Yang, Yutong Hong, Xiaoling Huang, Fen Ma, Yanhui Pan, Chuanzhen Li, Jiudi Zhong
KEYWORDS:
Esophageal Carcinoma, EORTC QLQ C-30, QLQ-OES18, Surgery, Quality of Life
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.13 No.9,
September
19,
2022
ABSTRACT: For patients with esophageal carcinoma (ESCA),
health-related quality of life (HRQoL) has now become an essential feature. To
examine the quality of life of preoperative and postoperative ESCA patients, we
used the European Organization for Research and Treatment of Cancer Quality of
Life Core Questionnaire (EORTC QLQ C-30) and the Quality of Life Questionnaire
Oesophageal 18 (QLQ-OES18). Using
the EORTC QLQ-C30 and the QLQ-OES18 questionnaire, the analysis of the quality of life scores of 246
patients with oesophageal cancer who were
operated on at the Sun Yat-sen University Cancer Centre during the
period 2013 to 2015 was carried out. Differences between pre- and post-surgical EORTC QLQ C-30 and QLQ-OES18
scores were examined using the Student’s t-test. Patients’ global health status
(QoL) decreased significantly one month after
the operation but gradually recovered within a year. In terms of the
role function, the emotional function, the cognitive function, and the
perception and function variants, EORTC QLQ-C30 and QLQ-OES18 scores increased statistically significantly, as did
clinical signs variables such as exhaustion, nausea, vomiting, pain,
sleeplessness, decreased appetite, stomach
pain, and economic hardship. After surgery, there was an improvement in
functional and symptom domains in esophageal carcinoma patients. EORTC QLQ-C30 and QLQ-OES18 can be used to assess the HRQoL before and after surgical procedures.