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has been cited by the following article:

• TITLE: Asymptomatic Mitral Regurgitation Caused by an Isolated Mitral Leaflet Cleft in a Young Adult: A Case Report

  AUTHORS: Mohamed Leye, Serigne Mor Beye, Momar Dioum, Sarah Mouna Coly, Désiré Alain Affangla, Djibril Marie Ba, Fatou Aw, Khadidiatou Gueye, Stéphanie Akani, Mouhamadou Bamba Ndiaye

  KEYWORDS: Mitral Regurgitation, Isolated Mitral Cleft, Adult Congenital Heart Disease, Senegal

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.12 No.2, February 25, 2022

  ABSTRACT: We report the case of an18-year-oldyoung manwithout previous medical history, who was referred for evaluation of an asymptomatic cardiac murmur. Physical examination found holosystolic 4-5/6 apical murmur with normal ECG. Bidimensionnal (2D) echocardiography revealed severe mitral regurgitation with thin mitral leaflets. Three dimensional (3D) Echocardiography done for better assessment of mitral valve regurgitation mechanism revealed an isolated mitral leaflet cleft, without signs of endocarditis or traumatic lesion. Regarding the absence of symptoms and excellent maximal exercise tolerance at stress echocardiography, a repair surgery wasn’t offered. Isolated mitral leaflet cleft is a rare congenital anomaly,in adults, the cleft may be an incidental finding that remains asymptomatic for years when the leak is well tolerated. 2D combined with 3D echocardiography is key for diagnosis and surgery guidance.