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https://doi.org/10.1056/NEJMoa055218

has been cited by the following article:

• TITLE: Bone Health in Pediatric Fracture Patients: A DEXA Study

  AUTHORS: Barbara Minkowitz, Jennifer Ristic, Leah Nadel, Meghan McDermott, Violet Wallerstein, Eileen Poletick

  KEYWORDS: Bone Health, Pediatric, Fracture, Vitamin D, DEXA, Osteoporosis, Osteopenia, Vitamin D Deficiency

  JOURNAL NAME: Open Journal of Orthopedics, Vol.12 No.2, February 23, 2022

  ABSTRACT: Vitamin D deficiency is widespread in children and is associated with increased fracture severity. Previous studies have shown mixed results on the impact of vitamin D supplementation on bone health parameters measured on dual-energy x-ray absorptiometry (DEXA) scan. This is the first longitudinal DEXA study in a pediatric fracture population. Pediatric fracture patients with vitamin D levels below 20 ng/mL were counseled to take vitamin D and calcium per a serum-based protocol. Patients underwent baseline DEXA within the initial 12 weeks post fracture and had follow-up scans at 6 and 12 months. 48 patients were enrolled, 32 patients completed two DEXA scans, and 19 completed three DEXA scans. There was a significant increase in lumbar spine BMC, TBLH BMD, and TBLH BMC between DEXA 1 and 2 (p 0.001). A positive trend in DEXA parameters is suggested between DEXA 1 and DEXA 3. Height adjusted z-scores (HAZ) were calculated which showed no statistical significance, p-values > 0.05. In this group, there are no significant changes in TBLH, BMC or BMD z-scores one year after fracturing despite vitamin D and calcium supplementation. This suggests that children returning to collision sports may be at continued risk for refracture and future studies are needed.