TITLE:
Oxone-Mediated Preparation of Ester Derivatives Using Indium(III) Triflate and Various Alcohols
AUTHORS:
Tomoko Mineno, Daiki Takano, Saika Komiya, Azusa Sato, Hisao Kansui
KEYWORDS:
Oxone, Oxidative Esterification, Benzaldehyde Derivatives, Ester Derivatives, Indium(III) Triflate, Alcohols
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.12 No.1,
February
17,
2022
ABSTRACT: Esters are known as one of the most fundamental chemical
moieties and also essentially useful components, especially for medicinal agents. Herein, using benzaldehyde and its
derivatives as starting materials, Oxone-mediated preparation of ester derivatives in the presence of a catalytic amount of indium(III) triflate is
described. Alcohols with various chain lengths, which functioned as solvents and substrates, were examined. Overall,
the oxidative esterification starting with
benzaldehyde derivatives possessing electron withdrawing groups proceeded
smoothly and gave sufficient yields, in comparison to the reactions with the
derivatives having electron donating groups.