TITLE:
Liver Cirrhosis Investigation Using Abdominal Ultrasound as Gold Standard Test and Some Bioclinical Markers with Different Levels of Diagnostic Accuracy in Chronic Liver Disease Patients between 1990 and 2004 at Teaching Hospital of Kinshasa, Democratic Republic of the Congo
AUTHORS:
Serge Malenga Mpaka, Aliocha Nkodila Natuhoyila, Michel Lelo Tshikwela, Sébastien Mbendi Nsukini, Charles Mbendi Nlombi, Simon Mbungu Fuele, Antoine Tshimpi Wola Yaba, Venant Tchokonte-Nana, Augustin Nge Okwe, Ingrid Cecile Djuikoue, Etienne Mokondjimobe, Benjamin Longo-Mbenza
KEYWORDS:
Ultrasound, Liver Cirrhosis, Haematological and Biochemical Tests, Diagnostic Performance, Central Africa
JOURNAL NAME:
Open Access Library Journal,
Vol.8 No.11,
November
30,
2021
ABSTRACT: Liver cirrhosis (LC) is an ultimate phase of chronic liver disease. The infor-mation from the abdominal ultrasound (aUS) is one of complementary biological and clinical tests of LC assessment in the lack of liver biopsy. The aim of this study was to compare levels of diagnostic accuracy of some bio-clinical markers for LC detection using an abdominal ultrasound as a surrogate Gold standard. This was a mixed approach of consecutive patients treated for gut diseases between 1990 and 2004 at Lomo Center. LC diagnosed by aUS and confirmed by histopathology was compared to LC diagnosed by Bioclinical tests under ROC, Chi-Square, and Logistics regression (for accuracy diagnosis, Sensitivity, Specificity, AUC, and kappa) at p