TITLE:
Distribution Characteristics of Drug Susceptibility Test Results of Tuberculosis and Non-Tuberculous Bacilli in Patients with Opportunistic Infections of AIDS
AUTHORS:
Qing Lin, Lida Mo, Xiaoye Su, Lihua Qin, Guosheng Su
KEYWORDS:
AIDS, Opportunistic Infections, Mycobacterium Tuberculosis Complex, Non-Tuberculous Mycobacteria
JOURNAL NAME:
Journal of Tuberculosis Research,
Vol.9 No.4,
November
10,
2021
ABSTRACT: Objective: To understand the distribution of drug
susceptibility test results of opportunistic infections of tuberculosis and
non-tuberculous bacilli in AIDS patients. Methods: The AIDS patients who
were hospitalized in our hospital from January 2016 to June 2019 were collected
as the research objects, and patients with opportunistic tuberculosis and
non-tuberculous bacilli from AIDS patients were screened for drug
susceptibility tests, and the distribution characteristics of drug
susceptibility were analyzed. Results:179 strains of tuberculosis and
non-tuberculous mycobacteria were isolated from the specimens of AIDS patients,
including 135 cases of tuberculosis mycobacteria and 44 cases of
non-tuberculous mycobacteria. In the results of the drug susceptibility test,
most strains of Mycobacterium
tuberculosis showed sensitivity to commonly used drugs, and a few
strains showed resistance; most strains of
non-tuberculous mycobacteria showed resistance, and a few strains showed sensitivity. Conclusion: AIDS opportunistic infection of Mycobacterium tuberculosis and
non-tuberculous mycobacteria have significant differences in drug sensitivity
test results. Timely detection and analysis are of great significance to the
diagnosis and treatment of the disease.