TITLE:
Successful Treatment of Spontaneous Rupture of the Spleen by Embolization of Splenic Artery in a Patient with Acute Promyelocytic Leukaemia and COVID-19 Infection
AUTHORS:
Olivera Markovic, Anica Divac, Filip Lukic, Davor Mrda, Ana Vidovic, Marija Zdravkovic, Borislav Toskovic
KEYWORDS:
Acute Promyelocytic Leukaemia, COVID-19, Embolisation of Splenic Artery, Splenic Rupture
JOURNAL NAME:
Open Journal of Emergency Medicine,
Vol.9 No.3,
July
6,
2021
ABSTRACT: Spontaneous rupture of the spleen (SRS) is a rare clinical entity with a potentially
poor medical outcome. In most cases, SRS is caused by neoplastic disorder. Acute
promyelocytic leukaemia is a rare but important cause of SRS that physicians are
required to assess for. We present a 28-year-old woman with APL and COVID-19 pneumonia,
who successfully underwent embolisation of the splenic artery for spontaneously
occurring splenic rupture during induction chemotherapy. After the intervention
the patient completed induction chemotherapy and achieved complete remission. Our
case demonstrates that emergent transcatheter arterial embolisation can be lifesaving
even in the unfavourable condition of a patient with severe immune deficiency.