Ahmadian, S., Sheshpari, S., Pazhang, M., Bedate, A.M., Beheshti, R., Abbasi, M.M., Nouri, M., Rahbarghazi, R. and Mahdipour, M. (2020) Intra-Ovarian Injection of Platelet-Rich Plasma into Ovarian Tissue Promoted Rejuvenation in the Rat Model of Premature Ovarian Insufficiency and Restored Ovulation Rate via Angiogenesis Modulation. Reproductive Biology and Endocrinology, 18, 1-13.
https://doi.org/10.1186/s12958-020-00638-4

has been cited by the following article:

• TITLE: Rejuvenation of Ovary and Thin Endometrium by Autologous PRP Injection in POR and Recurrent Implantation Failure

  AUTHORS: Yazhini Selvaraj, Kanchana Malaisamy

  KEYWORDS: Platelet Rich Plasma (PRP), Poor Ovarian Reserve (POR), Premature Ovarian Insufficiency (POI), Anti Mullerian Hormone (AMH), Antral Follicle Counts (AFC), Intra Cytoplasmic Sperm Injection (ICSI), Outpatient Procedure (OP)

  JOURNAL NAME: Advances in Sexual Medicine, Vol.11 No.1, January 30, 2021

  ABSTRACT: In India, the problem of infertility is growing and in the last 5 years, it has gone up to 20% - 30%. This ongoing prospective clinical study brings forth a novel, innovative, effective, simple, affordable, easily performed outpatient procedure (OP) and a promising therapeutic method in rejuvenating the Ageing Ovaries and Thin Endometrium, with autologous Platelet Rich Plasma (PRP). This clinical study proves to give a better result in rejuvenating Ovary and treating the Thin Endometrium. This pilot study included five women (28 - 44 years) with Poor Ovarian Response (POR), Premature Ovarian Insufficiency (POI) and Perimenopause and Thirty-nine women (22 - 43 years.) with recurrent implantation failure due to Thin Endometrium were subjected to autologous PRP instillation under Ultrasound Guidance, and Hysteroscopic guided PRP. After PRP, a significant output was obtained, with improved Anti Mullerian Hormone (AMH) and Antral Follicle Count (AFC) and out of five women three women conceived by Intra Cytoplasmic Sperm Injection (ICSI). PRP injected in women with Poor Ovarian Response found successful ovarian rejuvenation within 1 - 3 months and had a 60% of pregnancy rate, PRP into the endometrium had 53.8% successful pregnancies. We have not encountered any complications.