TITLE:
The Rhabdoid Tumor of the Kidney in Children—Cases Report
AUTHORS:
I. Tadmori, S. Benmiloud, M. Hbibi, M. Hida
KEYWORDS:
Child, Rhabdoid Tumor, Prognosis, Therapeutic Protocol
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.10 No.4,
November
5,
2020
ABSTRACT: Teratoid rhabdoid tumors are highly malignant, rare and aggressive. The prognosis is very poor,
with a pejorative and rapidly lethal evolution. The objective of this study was
to show diagnostic and therapeutic
approach through the report of four observations of rhabdoid tumor of the kidney in children, treated in the oncology
unit at the pediatric department CHU Hassan II Fez Morocco, collected over a period of 10 years. The ages of the
patients varied from 8 months and 5 and a half, with 3 girls and a boy. All children have abdominal distention with the discovery of a mass on
clinical examination. The patients were treated as nephroblastoma by neoadjuvant chemotherapy followed by enlarged
total nephrectomy. The pathological study confirmed the diagnosis of a teratoid rhabdoid tumor. Adjuvant chemotherapy was given in
all four children combined with radiotherapy in three cases. The evolution was
fatal in three children. Malignant rhabdoid tumors are a particular
pathological entity requiring a well codified therapeutic protocol to improve
survival which does not exceed 15% to 20%.