TITLE:
Physico-Chemical Evaluation and Hematological Responses in Clarias gariepinus (Burchell 1822) Juveniles Exposed to Adenium obesum Stem Bark Acute Bioassay
AUTHORS:
B. O. Muyiwa, N. S. Emmanuel, F. M. Yahuza, M. Aliyu, C. U. Inegbenosun, I. Musah
KEYWORDS:
Adenium obesum, Clarias gariepinus, Hematology, Toxicity
JOURNAL NAME:
Advances in Biological Chemistry,
Vol.10 No.2,
March
30,
2020
ABSTRACT: The experiment was conducted to evaluate the acute
toxicity of aqueous extract of Adenium obesum stem bark in juveniles of Clarias
gariepinus by assessing the hematological responses of the exposed groups
compared to the control in a static non-renewal bioassay for 96 hours. The
fishes (N = 180, mean weight and length 21.48 ± 3.32 g and 11.37 ± 1.23
cm) respectively were randomly distributed 10 (ten) fishes per group in
triplicates constituting six experimental groups as follows; G1 (Control), G2
(6.5 mg/l), G3 (7.8 mg/l), G4 (8.5 mg/l), G5 (9.5 mg/l) and G6 (11.5 mg/l). Red blood cell (RBC) count, packed cell
volume (PCV) and hemoglobin concentration were decreased significantly (P Adenium
obesum stem bark is toxic to erythrocytes while a converse adaptive
response in the white blood cells.