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https://doi.org/10.1016/0024-3205(79)90036-5

has been cited by the following article:

• TITLE: Synthesis and Crystal Structure Studies of Mitomycin C Dihydrate

  AUTHORS: Yingqi Feng, Yongshou Chen, Yixin Ren, Heng Zhang, Shuang Cao

  KEYWORDS: Crystal Structure, Dihydrate, Absolute Configuration, Mitomycin C

  JOURNAL NAME: Crystal Structure Theory and Applications, Vol.9 No.2, March 26, 2020

  ABSTRACT: The absolute configuration of mitomycin C was determinedby X-ray single crystal diffraction(CuKα), and a newcrystallinedihydrate of mitomycin C had been prepared. Theexperimentresultprovidesa definitive answerto the real absolute configuration of mitomycin C and may put an end to the disputethat bafflesresearchers for decades.At the same time, some contentious structuresabout the mitomycin C inAmerican PharmacopoeiaUSP36-NF31,Chinese pharmacopoeia2015edtionand numbers ofliteratures are marked. The absolute configurationisalso verifiedby1D (1Hand13C) and 2D (HSQC, HMBC,1H-1HCOSYandNOESY) NMR studiesindirectly. Powder X-ray diffraction (PXRD) pattern of themitomycin C dihydrateis similar to that calculated forit, whichsuggests that the purityofsampleis excellent.